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[This corrects the article DOI: 10.1371/journal.pone.0282492.].
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0320868 | PLOS |
Brain Behav
September 2025
School of Pharmacy and Medical Technology, Putian University, Putian, China.
Background: Recent research has started to uncover an important connection between immune system activity and cognitive abilities. Although correlative associations have been documented, the causal mechanisms connecting specific immune cell subpopulations to cognitive capabilities remain insufficiently characterized. Our research aimed to determine directional relationships between distinct immune cell subtypes and cognitive function, potentially identifying targets for immunomodulatory interventions.
View Article and Find Full Text PDFJ Vet Intern Med
September 2025
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, California, USA.
Background: Echocardiographic reference intervals for Quarter Horses are infrequently reported.
Objectives: To provide standard echocardiographic measurements for sedentary Quarter Horses and evaluate the relationship between physical characteristics (body weight, age, sex) and echocardiographic measurements.
Animals: Forty-one sedentary Quarter Horses, free of cardiac disease, from a university research herd.
J Am Coll Cardiol
September 2025
Institute of Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiologic Sciences and Public Health, University of Brescia, Brescia, Italy. Electronic address:
Secondary mitral regurgitation (SMR) is common in patients with heart failure (HF). Although randomized clinical trials have been focused on the treatment of severe SMR, the prognostic role and potential for treatment of moderate SMR cannot be overlooked. The randomized RESHAPE-HF2 trial included patients with moderate and severe SMR with consistent findings in both groups, raising the hypothesis that transcatheter correction of moderate SMR could have beneficial effects, although this needs further investigation.
View Article and Find Full Text PDFStat Med
September 2025
Service de Biostatistique-Bioinformatique, Hospices Civils de Lyon, Lyon, France.
Single-arm control trials are increasingly proposed as a potential approach for treatment evaluation. However, the limitations of this design restrict its methodological acceptability. Regulatory agencies have raised concerns about this approach, although it is sometimes required in applications based solely on such studies.
View Article and Find Full Text PDFPol Merkur Lekarski
September 2025
FACULTY OF NURSING, UNIVERSITY OF KUFA, NAJAF, IRAQ.
Objective: Aim: To investigate the role of serum vitamin D3 in the pathogenesis and diagnosis for hypothyroidism..
Patients And Methods: Materials and Methods: Cross-sectional study was conducted at the Outpatient Analytics Center of Al-Nokhba and Al-Sadder Teaching Hospital, Najaf, Iraq, between October 2021 and February 2022.