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http://dx.doi.org/10.1007/s00429-025-02898-5 | DOI Listing |
Clin Rheumatol
September 2025
Histocompatibility Department, Hedi Chaker UH, University of Sfax, Sfax, Tunisia.
Objective: Systemic sclerosis (SSc) is a complex autoimmune connective tissue disease. Genetic factors may play a pivotal role in determining susceptibility to these disorders. HLA associations with SSc, especially HLA class II, were investigated in different populations but not in Tunisia.
View Article and Find Full Text PDFSci Justice
September 2025
Department of Analytical, Environmental and Forensic Sciences, King's College London, London, UK.
ISO 21043 is a new international standard for forensic science. It provides requirements and recommendations designed to ensure the quality of the forensic process. It includes Parts on: 1 vocabulary; 2 recovery, transport, and storage of items; 3 analysis; 4 interpretation; and 5 reporting.
View Article and Find Full Text PDFBMJ Open
September 2025
Upstream Lab, MAP Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, Unity Health Toronto, Toronto, Ontario, Canada
Objective: This study validates the previously tested Screening for Poverty And Related social determinants to improve Knowledge of and access to resources ('SPARK Tool') against comparison questions from well-established national surveys (Post Survey Questionnaire (PSQ)) to inform the development of a standardised tool to collect patients' demographic and social needs data in healthcare.
Design: Cross-sectional study.
Setting: Pan-Canadian study of participants from four Canadian provinces (SK, MB, ON and NL).
Rev Cardiovasc Med
August 2025
Cardiovascular Surgery Department, Ankara Bilkent City Hospital, 06800 Ankara, Turkey.
Background: This study aimed to investigate the performance of two versions of ChatGPT (o1 and 4o) in making decisions about coronary revascularization and to compare the recommendations of these versions with those of a multidisciplinary Heart Team. Moreover, the study aimed to assess whether the decisions generated by ChatGPT, based on the internal knowledge base of the system and clinical guidelines, align with expert recommendations in real-world coronary artery disease management. Given the increasing prevalence and processing capabilities of large language models, such as ChatGPT, this comparison offers insights into the potential applicability of these systems in complex clinical decision-making.
View Article and Find Full Text PDFAlpha Psychiatry
August 2025
Information Sciences and Technology, George Mason University, Fairfax, VA 22030, USA.
Background: Herein, we report on the initial development, progress, and future plans for an autonomous artificial intelligence (AI) system designed to manage major depressive disorder (MDD). The system is a web-based, patient-facing conversational AI that collects medical history, provides presumed diagnosis, recommends treatment, and coordinates care for patients with MDD.
Methods: The system includes seven components, five of which are complete and two are in development.