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Assessing the utility of SISCOM and PISCOM in mapping the epileptogenic zone for epilepsy surgery: A comparative outcome-based study.
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Amrita Advanced Centre for Epilepsy (AACE), Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India; Department of Neurology, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India. Electronic address:
Intro: Ictal SPECT imaging stands out among non-invasive tools as the primary presurgical method for spatially defining the seizure network. Advanced image analysis methods like SISCOM and PISCOM improve the interpretation of SPECT images. However, research on their comparative utility, significance of their overlapping areas, and optimal z-scores for mapping/localizing the seizure onset zone is limited.
View Article and Find Full Text PDFPeri-ictal imaging abnormalities in non-convulsive status epilepticus: A systematic review and meta-analysis comparing magnetic resonance imaging and computed tomography perfusion.
Epilepsia
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Epilepsy Center Hessen, Department of Neurology, Philipps University Marburg, Marburg, Germany.
Objective: To assess and compare the detection rates of peri-ictal abnormalities using magnetic resonance imaging (MRI) and computed tomography perfusion (CTP) in patients with non-convulsive status epilepticus (NCSE).
Methods: We conducted a systematic literature search in five databases up to February 2025. Studies reporting peri-ictal MRI abnormalities (PMAs) or cerebral perfusion abnormalities (CPAs) in patients with NCSE were included.
Pontine hyperperfusion associated with ictal central apnea.
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Comprehensive Epilepsy Center, Northwestern Memorial Hospital, Chicago, Illinois, USA.
We report ictal SPECT findings in a patient with focal epilepsy and ictal central apnea (ICA). We describe the history, EEG findings, and SPECT analysis of a 38-year-old female with left posterior quadrant epilepsy post intracerebral hemorrhage due to ruptured aneurysm, whose seizures are accompanied by ICA. The patient underwent continuous EEG monitoring as a presurgical candidate for her epilepsy, during which several typical seizures associated with ICA were captured.
View Article and Find Full Text PDFImaging of Status Epilepticus.
J Clin Med
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Department of Neurology, Neurocritical Care and Neurorehabilitation, Christian Doppler University Hospital, Centre for Cognitive Neuroscience, Member of the European Reference Network EpiCARE, Paracelsus Medical University of Salzburg, 5020 Salzburg, Austria.
MRI plays an increasingly important role in the diagnosis of status epilepticus (SE). Approximately half of patients with SE do not have pre-existing epilepsy, and the cause of de novo SE is frequently unknown. The role of MRI in the identification of causes of SE is invaluable.
View Article and Find Full Text PDF