Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
A 38-year-old male with Gilbert syndrome presented with acute cholecystitis, jaundice, and elevated liver enzymes. This case highlights the importance of genetic testing for unexplained jaundice, avoiding misdiagnosis, and guiding personalized treatment for Gilbert syndrome.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882763 | PMC |
| http://dx.doi.org/10.1002/ccr3.70290 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Modeling human retinal ganglion cell axonal outgrowth, development, and pathology using pluripotent stem cell-based microfluidic platforms.
Proc Natl Acad Sci U S A
September 2025
Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202.
Retinal ganglion cells (RGCs) are highly compartmentalized neurons whose long axons serve as the sole connection between the eye and the brain. In both injury and disease, RGC degeneration occurs in a similarly compartmentalized manner, with distinct molecular and cellular responses in the axonal and somatodendritic regions. The goal of this study was to establish a microfluidic-based platform to investigate RGC compartmentalization in both health and disease states.
View Article and Find Full Text PDFBayesian estimation of HIV acquisition dates for prevention trials.
mBio
September 2025
Fred Hutchinson Cancer Center, Vaccine and Infectious Disease Division, Seattle, Washington, USA.
Accurate timing estimates of when participants acquire HIV in HIV prevention trials are necessary for determining antibody levels at acquisition. The Antibody-Mediated Prevention (AMP) Studies showed that a passively administered broadly neutralizing antibody can prevent the acquisition of HIV from a neutralization-sensitive virus. We developed a pipeline for estimating the date of detectable HIV acquisition (DDA) in AMP Study participants using diagnostic and viral sequence data.
View Article and Find Full Text PDFWhen Zoonosis Meets Genetics: Brucellosis and Gilbert Syndrome in a Young Woman From Rural Nepal.
Cureus
August 2025
Department of Internal Medicine, Maimonides Medical Center, Brooklyn, USA.
Brucellosis is a neglected zoonotic infection in Nepal that is often underdiagnosed, particularly in regions considered to have low prevalence. Its presentation can mimic autoimmune or hepatic disorders, complicating timely diagnosis and management. Coexistence with hereditary conditions such as Gilbert syndrome can further obscure the clinical picture.
View Article and Find Full Text PDFUsing a Brief Body Sway Assessment Device to Track Balance Differences across the Huntington's Disease Integrated Staging System Spectrum.
Mov Disord Clin Pract
September 2025
Department of neuroscience, UC San Diego, San Diego, California, USA.
Background: Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by a mutation in the huntingtin gene on chromosome 4, leading to progressive cognitive decline, motor impairment, and functional disability. Although balance impairment is recognized in HD, its onset and evolution with disease stage remain poorly understood.
Objective: The aim was to track the onset and evolution of balance impairment in HD with progression of disease stage using the BTrackS Balance Plate.
Peri-hilar cholangiocarcinoma: results from the UK nationwide CAPBIL study.
HPB (Oxford)
August 2025
Nottingham University Hospitals NHS Trust, Nottingham, UK. Electronic address:
Background: The role of liver transplantation as a treatment option for de novo resectable peri-hilar cholangiocarcinoma (pCCA) is controversial. This study investigated the outcomes following resection of early-stage pCCA in the UK.
Methods: Patients undergoing resection for pCCA between 2014 and 2022 across 22 UK centres were included.