On the spatial synaptic propagation of excitations induced by repetitive microstimulation pulses in the mouse visual cortex.

The spatial synaptic propagation of membrane excitation in response to the trains of microstimulation pulses applied to the cortical layer II/III in the mouse cerebral tissue slices was analyzed by means of the voltage-sensitive dye imaging and the numerical simulation with a one-dimensional network model. The present model was able to simulate the spatial dynamics of the post-synaptic component of response induced by the repetitive current pulses.