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Introduction: Gestational diabetes mellitus (GDM) is a growing global concern. GDM increases the risk of complications in both mothers and infants, including preeclampsia, macrosomia, and a higher likelihood of developing type 2 diabetes later in life. This study aimed to assess whether integrating case-based learning (CBL) with traditional education could improve glycemic control and patient outcomes in women with GDM.
Methods: This non-parallel quasi-experimental study compared CBL interventions with traditional education in GDM women. Pregnant women from September 2022 to March 2023 received only traditional education (control group), whereas those from April to September 2023 received both case-based and traditional education (intervention group). The primary outcomes included fasting and 2-hour postprandial blood glucose level changes after the intervention. The secondary outcomes included self-management behavior changes (Self-Management Scale for Women with GDM), self-efficacy (Pregnancy Exercise Self-Efficacy Scale), GDM understanding (self-developed questionnaire), satisfaction, pregnancy weight gain, and macrosomia incidence.
Results: A total of 140 GDM women were included, with the intervention and control groups containing 70 participants each. The intervention group showed significantly greater reductions in fasting and 2-hour postprandial blood glucose levels than the control group (<0.001). In addition, the intervention group demonstrated notable improvements in self-management behaviors, GDM knowledge, and patient satisfaction. The incidence of macrosomia was also significantly lower in the intervention group (1.6% vs 10.8%, =0.034), indicating better neonatal outcomes.
Conclusion: CBL could be incorporated into traditional education in GDM women to improve their self-management and self-efficacy for better glycemic control and pregnancy outcomes. Healthcare providers should be educated on the CBL and relevant policies should be developed to facilitate the implementation of CBL in the clinical practice.
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http://dx.doi.org/10.2147/PPA.S503359 | DOI Listing |
Environ Sci Technol
September 2025
Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P.R. China.
Ambroxol (AMB), a common expectorant, enters aquatic environments via wastewater, yet its ecological risks remain unclear. Under UV exposure (15 mJ·cm, λ = 185-400 nm), AMB undergoes photolysis, among the photoproducts, 4-((2-amino-3-bromobenzyl)amino) cyclohexanol (P1) and 2-amino-3,5-dibromobenzaldehyde (DBA) are major species, comprising over 50% of the total photoproduct peak area at the photolytic plateau. Acute toxicity tests with AMB, P1, and DBA in four aquatic species at different trophic levels revealed: the highest sensitivity in (LC = 0.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
The Third Affiliated Hospital of Jinzhou Medical University, No. 2, Section 5, Heping Road, Linghe District, Jinzhou, City, Liaoning Province, 121000, PR China. Electronic address:
We explored the role of Polygonatum Rhizoma polysaccharide (PRP) in delaying aging and improving Alzheimer's disease (AD) and revealed its potential molecular mechanism. Through chemical characterizations to clarify the physicochemical properties of PRP, it was found that PRP mainly consists of mannose, glucose, galactose, and arabinose, with molecular weights ranging from 7.4 × 10 to 9.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China; Key Laboratory of Traditional Chinese Medicine Classical Theory, Ministry of Education, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China. Electronic address:
The thermosensitive transient receptor potential (Thermo-TRP) channel proteins comprise TRPA1, TRPV1-V4, and TRPM8. TRP channels are mainly situated on cellular surfaces and react to a range of external factors, including heat, cold, acidity, osmotic pressure, chemical signals, and flavors, as well as intracellular signals such as Ca, Na, and cytokines. The thermo-TRP channels are associated with many physiological signal pathways, with their distinct molecular structure making them promising drug targets for respiratory diseases.
View Article and Find Full Text PDFAsian J Psychiatr
September 2025
National-Local Joint Engineering Research Center of Rehabilitation Medicine Technology, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China; Rehabilitation Industry Institute, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China; Traditional Chinese Medicine Re
Background: Amnestic mild cognitive impairment (aMCI) is characterized by marked episodic memory decline. The hippocampus is essential for episodic memory, and integration of information within its subregions is central to this process. This study examined how alterations in hippocampal subregional network relate to episodic memory impairment in aMCI.
View Article and Find Full Text PDFNurse Educ Pract
September 2025
Department of Allied Health Education and Digital Learning, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan, ROC. Electronic address:
Aim: To evaluate the effectiveness of the CARES-MFW (Clinical Augmented Reality Education Simulation for Malignant Fungating Wounds) app in enhancing nurses' knowledge and clinical reasoning in the care of MFWs.
Background: Malignant fungating wounds (MFWs) affect many patients with advanced cancer, with nearly 50 % dying within six months of diagnosis. These wounds often present with heavy exudate, pain, malodor and bleeding, leading to profound physical and psychosocial distress.