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Intense sub-daily precipitation on the Tibetan Plateau (TP) can trigger a cascade of natural hazards (flash floods, debris flows, etc.), causing significant environmental impacts. Current precipitation products for the TP often lack sufficient spatial or temporal resolution, hindering accurate characterization and mitigation of precipitation-related hazards. Here, we carry out 10-year (2012-2021, June to September) convection-permitting model simulations based on the Weather Research and Forecasting (WRF) model over the TP. We adopt four one-way nested domains, with the innermost domain providing a 1-km, hourly resolution over the southeastern TP. Model performance is enhanced using a spectral nudging scheme. Our simulated precipitation data are compared against in-situ rain gauge observations and state-of-the-art gridded precipitation products (i.e., HAR v2, ERA5-Land, and IMERG) over the southeastern TP. Our precipitation dataset demonstrates superior accuracy in mean absolute error, root mean square error, and bias, compared to the other three products. It effectively captures the key feature of the diurnal precipitation cycle and the non-monotonic dependence of precipitation on complex topography over the southeastern TP.
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http://dx.doi.org/10.1038/s41597-025-04654-0 | DOI Listing |
Langmuir
September 2025
Department of Applied Sciences, National Institute of Technology Delhi, Delhi 110036, India.
The degradation of colorless tetracycline hydrochloride (TCH), a widely used antibiotic, is a significant environmental concern due to its persistence in aquatic systems. The zinc sulfide (ZnS) nanoparticle fabricated melamine-formaldehyde polymer (MFP)-based nanocomposite (ZnS-MFP) was prepared via a hydrothermal polymerization method, followed by surface modification through a simple precipitation route. The degradation of TCH through photocatalysis adheres to pseudo-first-order kinetics with a significantly faster rate under natural sunlight than under artificial bulb light.
View Article and Find Full Text PDFDiabetes Obes Metab
September 2025
Department of Applied Health Sciences, University of Birmingham, Birmingham, UK.
Aim: Sodium-glucose co-transporter-2 inhibitors (SGLT2i) offer significant cardiorenal benefits for people with type 2 diabetes (PwT2D). However, concerns remain regarding their association with diabetes-related ketoacidosis (DKA). (1) To compare demographics, precipitating factors, biochemical features, management, and outcomes of acute DKA admissions between SGLT2i users (n = 267) and non-users (n = 793) with T2D.
View Article and Find Full Text PDFJ Vasc Surg Cases Innov Tech
December 2025
Department of Cardiovascular Surgery, Ogaki Municipal Hospital, Ogaki, Japan.
Pancreaticoduodenal artery (PDA) aneurysm is rare. A 79-year-old man with an abdominal aortic aneurysm and celiac artery stenosis caused by median arcuate ligament compression underwent endovascular aneurysm repair. On postoperative day 1, the patient experienced sudden abdominal pain and hypotension.
View Article and Find Full Text PDFMol Genet Metab Rep
December 2025
Pediatric Critical Care Medicine, Department of Pediatrics NewYork-Presbyterian Morgan Stanley Children's Hospital, Columbia University Medical Center, New York, NY, United States of America.
encodes NADH: ubiquinone oxidoreductase core subunit V1, a key component of mitochondrial Complex 1. Biallelic pathogenic variants in this gene produce a broad and variable phenotypic spectrum in affected individuals, including ophthalmoplegia, developmental delays, brain imaging abnormalities, and recurrent episodes of emesis and lactic acidemia. We report female siblings compound heterozygous for two missense variants (Arg40Gln, Val245Met) in with unusual presentations of this condition.
View Article and Find Full Text PDFCureus
August 2025
Department of Research for Spine and Spinal Surgery, Fukushima Medical University, Fukushima, JPN.
Dural tears are a well-known complication of spinal surgery. While most occur intraoperatively and are promptly identified, some are overlooked or develop postoperatively. Delayed-onset dural tears are relatively rare but can result in significant neurological complications, including cauda equina syndrome (CES).
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