98%
921
2 minutes
20
Objective: There is no consensus on the optimum time for an EEG after the first seizure. We sought to investigate whether the timing of an EEG after a first unprovoked seizure influences its diagnostic yield.
Methods: A retrospective analysis was conducted at a tertiary hospital in Australia. Adult patients who presented with a first unprovoked seizure were studied. Using multivariable logistic regression, we investigated the association of EEG timing, seizure presentation, and risk factors for epilepsy with the presence of interictal epileptiform discharges (IED) in the EEG as the outcome. The chi-square test compared EEG yields across each week after the seizure.
Results: Among 452 patients, the time from seizure to EEG did not show a statistically significant impact on the presence of IEDs (OR = 1, 95 % CI 0.99-1, p = 0.095). The yield of epileptiform abnormalities generally declined over time but was not statistically significant across weeks (p = 0.40). A modest but significant relationship was found between age and the likelihood of detecting IEDs, with older age associated with a lower yield of abnormalities (OR = 0.98, 95 % CI 0.973-0.997, p = 0.016).
Conclusion: Our results suggest that the timing of the EEG following the first unprovoked seizure does not significantly impact the diagnostic yield.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.yebeh.2025.110311 | DOI Listing |
Clin Toxicol (Phila)
August 2025
Clinical Toxicology Unit, Princess Alexandra Hospital, Brisbane, Australia.
Introduction: Seizures are a marker of severe toxicity following overdose. Research characterising toxicological seizures is limited. We aim to study toxicological seizures, causative agents, and recurrence.
View Article and Find Full Text PDFAnn Med Surg (Lond)
September 2025
Faculty of Medicine, University of Khartoum, Khartoum, Sudan.
Background: Epilepsy is a chronic non-communicable disease defined as recurrent and unprovoked seizures. Epilepsy causes a wide range of challenges that affect the patient's quality of life (QoL). This study aimed to assess the quality of life and associated factors among patients with epilepsy in Khartoum State, Sudan.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
September 2025
Osh State University, Osh, Kyrgyz Republic.
Epileptic seizures are defined as transient, abnormal, excessive synchronous activity of neurons in the brain, which can be provoked or unprovoked. While unprovoked seizures are common in many idiopathic epilepsies, provoked seizures are usually caused by acute or chronic CNS conditions. These often include cerebrovascular diseases such as ischemic stroke, intracerebral and subdural hemorrhages, posterior reversible encephalopathy syndrome, and cerebral venous sinus thrombosis.
View Article and Find Full Text PDFEur J Neurol
September 2025
The Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
Background: Abnormal electroencephalograms (EEGs) are a known risk factor for additional seizures following a first unprovoked seizure (FUS). This study assessed whether early or late EEGs after a FUS predict subsequent seizures in pediatric and adult patients.
Methods: This retrospective study included patients who underwent EEGs after a FUS between 4/2011 and 12/2015, categorized into children (≤ 16 years) and adults.
Epilepsia
August 2025
EEG & Epilepsy Unit, Department of Clinical Neurosciences, University Hospital of Geneva, Geneva, Switzerland.
Objective: A joint International Federation of Clinical Neurophysiology-International League Against Epilepsy (IFCN-ILAE) Taskforce was created to explore the published evidence for initial EEG recordings in the evaluation of patients who experienced their first unprovoked seizure, and to determine the diagnostic value of EEG in supporting the diagnosis of epilepsy.
Methods: We conducted a systematic literature review, with two independent authors screening each study. We extracted seizure recurrence data among patients with EEG showing interictal epileptiform discharges (IEDs) vs those with normal or nonspecific-abnormal EEG results.