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The incidental learning index based on Similarities subtest (IL-Sim) from the Wechsler Adult Intelligence Test-Fourth Edition (WAIS-IV) has shown promise as a screening measure for memory impairment. We aimed to examine the reliability, convergent and divergent validity, and the utility of IL-Sim index in classifying at least mild and severe memory impairment. One hundred and fifty-three Veterans completed the WAIS-IV Similarities subtest and Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) as part of their clinical evaluations. IL-Sim had acceptable internal consistency (Cronbach's = .85). Among RBANS indices, IL-Sim had the largest association with the Delayed Memory Index ( = .69), followed by the Immediate Memory Index ( = .59), and relatively smaller associations with non-memory indices (s = .26-.38). For both younger (ages 40-69) and older (ages 70-87) adults, IL-Sim had excellent discriminability between patients without memory problems and those with at least mildly or severely impaired RBANS memory (AUC = .83-.87). To enhance the ease of interpretation for IL-Sim scores, we presented logistic regression-derived probabilities across multiple base rates for each age group and impairment severity. IL-Sim showed strong convergent and divergent validity and discriminated along the memory impairment continuum highlighting its promise as an efficient screening measure of memory.
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http://dx.doi.org/10.1080/23279095.2025.2466187 | DOI Listing |
Cien Saude Colet
August 2025
Faculdade Ciências Médicas de Minas Gerais. Alameda Ezequiel Dias 275, Centro. 30130-110 Belo Horizonte MG Brasil.
The aim is to identify the prevalence and main factors associated with self-reported poor sleep quality in Brazilian adults aged 50 and older. A cross-sectional study with participants from the Brazilian Longitudinal Study of Aging (2019-2021). A total of 9,849 participants aged 50 and older with complete information for the variables of interest were included.
View Article and Find Full Text PDFDisabil Rehabil Assist Technol
September 2025
School of Drama, Film and Television, Shenyang Conservatory of Music, Shenyang, China.
This study examines how choral singing functions as a mechanism for sustaining ritual practice and reinforcing cultural identity. By integrating perspectives from musicology, social psychology, and cognitive science, it explores how collective vocal performance supports emotional attunement, group cohesion, and symbolic memory in culturally diverse contexts. A mixed-methods approach was applied, combining ethnographic observation, survey-based data, and cognitive measures with AI-informed frameworks such as voice emotion recognition and neural synchrony modeling.
View Article and Find Full Text PDFJ Gerontol A Biol Sci Med Sci
September 2025
Department of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing, MI.
Background: Poor olfaction may be associated with incident heart failure (HF) in older adults, but empirical evidence is scant.
Methods: We included 5,217 participants free of clinical HF and with a smell assessment in 2011-2013 from the Atherosclerosis Risk in Communities Study. Olfaction was measured by the 12-item Sniffin' Sticks odor identification test and defined as good (score 11-12), moderate (9-10), or poor (≤8).
JAMA Psychiatry
September 2025
Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville.
Importance: Behavioral variant frontotemporal dementia (bvFTD), the most common subtype of FTD, is a leading form of early-onset dementia worldwide. Accurate and timely diagnosis of bvFTD is frequently delayed due to symptoms overlapping with common psychiatric disorders, and interest has increased in identifying biomarkers that may aid in differentiating bvFTD from psychiatric disorders.
Objective: To summarize and critically review studies examining whether neurofilament light chain (NfL) in cerebrospinal fluid (CSF) or blood is a viable aid in the differential diagnosis of bvFTD vs psychiatric disorders.
Metab Brain Dis
September 2025
Department of Neuroscience, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Brain ischemia is a major global cause of disability, frequently leading to psychoneurological issues. This study investigates the effects of 4-aminopyridine (4-AP) on anxiety, cognitive impairment, and potential underlying mechanisms in a mouse model of medial prefrontal cortex (mPFC) ischemia. Mice with mPFC ischemia were treated with normal saline (NS) or different doses of 4-AP (250, 500, and 1000 µg/kg) for 14 consecutive days.
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