Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11841198 | PMC |
| http://dx.doi.org/10.1002/hem3.70094 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Salvage treatment of a metastatic colorectal cancer with pMMR/MSS in a 21-year-old man: a case report.
Front Oncol
August 2025
Department of Medical Oncology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.
In metastatic colorectal cancer (mCRC) patients with proficient mismatch repair (pMMR)/microsatellite stability (MSS), beyond third-line therapies were extremely limited. Here, we reported a case of a 21-year-old male patient with pMMR/MSS mCRC who failed to respond to both first- and second-line treatment and subsequently received non-standard third-line therapy at a local hospital. This patient was referred to our hospital, and we initiated salvage therapies.
View Article and Find Full Text PDFRecurrent Grade I Parafalcine Meningioma: Management Challenges and Genomic Insights.
Cureus
August 2025
Radiation Oncology, Thomas Jefferson University Hospital, Philadelphia, USA.
While World Health Organization (WHO) grade I meningiomas are typically slow growing and associated with favorable prognoses, a subset may exhibit unexpectedly aggressive behavior and resistance to conventional treatment approaches. Recurrent grade I meningiomas, in particular, are associated with a poorer prognosis despite their benign histological classification, underscoring the need for advanced genomic and radiomic analyses to refine diagnostic accuracy. We present a case of a 52-year-old female with a grade I parafalcine meningioma initially deemed nonaggressive, but ultimately recurred multiple times over several years despite undergoing repeated craniotomies and several courses of radiosurgery.
View Article and Find Full Text PDFAdenoid Cystic Carcinoma Treated With Salvage ZAP-X Radiosurgery in Elderly Patients: A Report on a Case Series.
Cureus
August 2025
Department of Oncology, University of Warmia and Mazury in Olsztyn, Olsztyn, POL.
Management of recurrent adenoid cystic carcinoma (ACC) in elderly patients remains challenging due to comorbidities, functional impairments, and anatomically complex tumor locations that complicate surgical access and increase operative risk. The ZAP-X Gyroscopic Radiosurgery System (ZAP Surgical Systems, Inc., San Carlos, CA, USA) offers a highly precise, non-invasive treatment modality, potentially suitable for salvage therapy in previously irradiated fields and in medically inoperable patients.
View Article and Find Full Text PDFAn Innovative Reconstruction Technique for Proximal Tibia Grade 3 Giant Cell Tumor: The Sky Roof Reconstruction Approach.
Cureus
August 2025
Orthopedics, All India Institute of Medical Sciences, Jodhpur, Jodhpur, IND.
Giant cell tumor (GCT) of the bone, although benign, demonstrates local aggressiveness, a potential for recurrence, and, in rare instances, malignant transformation. Functional preservation is crucial in cases involving the articular surface, often utilizing the Sandwich Technique. We propose an enhanced reconstruction method using the inner table of the iliac crest in a reverse fashion, offering a more anatomically contoured proximal tibial plateau and reducing donor site morbidity compared to tricortical iliac crest grafting.
View Article and Find Full Text PDFSalvage repair of complete aortic root detachment after Bentall procedure: a case of LVOT elongation.
Multimed Man Cardiothorac Surg
September 2025
Department of Cardiovascular Surgery, Marmara University Pendik Research and Training Hospital, Istanbul, Turkey.
Complete detachment of the aortic root following a Bentall procedure is an exceptionally rare complication. The vast majority of reported cases are secondary to prosthetic valve endocarditis or underlying vasculitis. Currently, the most reliable treatment for aortic root dehiscence-particularly in the context of prosthetic valve endocarditis-is repeat root replacement, typically via a second Bentall procedure or with the use of a homograft or allograft.
View Article and Find Full Text PDF