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Objective: This study aims to determine the prevalence of electrolyte disturbances in children hospitalized in the pediatric intensive care unit (PICU) of Rajendra Institute of Medical Sciences (RIMS), a tertiary care center in Ranchi, India, and to evaluate related factors like pneumonia, heart disease, meningitis/encephalitis, and others.
Methods: Serum electrolyte levels (sodium, potassium, calcium, magnesium) were obtained from 110 patients admitted to the PICU at RIMS. Statistical analyses were conducted to identify the prevalence and association of disturbances with specific diseases.
Results: Sodium disturbances was most common (32 cases, 29%), with 28 (25.45%) patients exhibiting hyponatremia and four exhibiting hypernatremia (3.63%). Hypokalemia (10 cases, 9.09%) was associated predominantly with central nervous system (CNS) disorders. Hypocalcemia (26 cases, 23.63%) was most frequently linked to respiratory disorders. Hypomagnesemia cases (18, 16.36%) were also prevalent.
Conclusion: Electrolyte disturbances are common in critically ill pediatric patients and are associated with various systemic disorders, emphasizing the need for regular monitoring in the PICU.
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http://dx.doi.org/10.7759/cureus.77698 | DOI Listing |
Rev Med Suisse
August 2025
Unité de nutrition clinique, Service de gastroentérologie et hépatologie, Hôpitaux universitaires de Genève, 1211 Genève 14.
Refeeding syndrome (RFS), which is often underdiagnosed, is a preventable condition that can be fatal if not managed early. It may occur after nutrition is reintroduced in malnourished patients or those who have experienced a prolonged reduction in food intake. As a result of the metabolic shift from a catabolic to an anabolic state, RFS is characterized by electrolyte disturbances and vitamin deficiencies, which can lead to severe clinical complications.
View Article and Find Full Text PDFBackground: Malaria is one of the most infectious diseases, and electrolyte imbalance and mineral disturbances are common clinical manifestations. This study aimed to explore the effect of malaria on biochemical parameters in Sudanese patients with severe falciparum malaria.
Methods: A case-control study was conducted in the clinical laboratory of the Kosti Teaching Hospital between August 2022 and January 2023.
Endocrinol Diabetes Metab Case Rep
July 2025
Department of Internal Medicine, Medical City Arlington, Arlington, Texas, USA.
Summary: Hypercalcemia is a prevalent electrolyte disturbance commonly associated with primary hyperparathyroidism, cancer, or medication adverse effects. Thiazide diuretics reduce urinary calcium excretion, increasing calcium reabsorption and hypercalcemia. Tirzepatide, a dual GIP and GLP-1 receptor agonist, is increasingly used for type 2 diabetes and obesity.
View Article and Find Full Text PDFCureus
August 2025
Department of Paediatrics, Queen Elizabeth Hospital, Hong Kong, HKG.
Hyponatremia and hyperkalemia, though uncommon in infancy, are potentially life-threatening electrolyte disturbances. We discuss a case of secondary pseudohypoaldosteronism (PHA) in a six-month-old male presenting with recurrent vomiting, severe hyponatremia (119 mmol/L), hyperkalemia (6.6 mmol/L), and metabolic acidosis (bicarbonate: 9 mmol/L).
View Article and Find Full Text PDFPhysiol Plant
September 2025
State Key Laboratory of Rice Biology and Breeding, China National Rice Research Institute, Hangzhou, China.
The Gα subunit RGA1, a crucial component of heterotrimeric G proteins, has been well-documented to enhance drought resistance in rice seedlings. However, its role during the reproductive stages has remained unexplored. This study aimed to investigate the function of RGA1 in mitigating drought-induced defects in anther and pollen development during pollen mother cell meiosis with Zhonghua 11 (WT), a Gα-deficient mutant (d1), and an RGA1-overexpressing line (OE-1).
View Article and Find Full Text PDF