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Today, when nanotechnological innovation, in particular, faces stringent regulations, the question arises concerning a tool that can quantify individual interventions and thus complement current knowledge in the diffusion theory of innovation. This paper examines the complex nature of innovation diffusion in a rapidly evolving technological environment. The research presents current knowledge in the field linking diffusion of innovation theory and the basic epidemiological model of SIR (Susceptible, Infected, Recovered). Epidemiological models, originally developed to study the spread of infectious diseases, offer intriguing parallels to innovation diffusion due to shared characteristics in propagation dynamics. Integrating the SIR epidemiological model into the current theoretical framework allows the SIR model to be considered as a tool capable of filling current gaps in the literature. Nanotechnological innovations are chosen because of their significant impact on society, which faces unique market entry challenges. Within the framework of high interdisciplinarity, nanotechnologies, like viruses, tend to 'mutate' into different industries where their 'infectivity' varies. The case of nanotechnology serves to illustrate the usefulness of the proposed model and shows how factors that influence the spread of viruses can similarly affect the adoption of technological innovations. Similar characteristics in the propagation framework between innovations and viruses can serve as one of many arguments for the use of the SIR model in this field. Using an integrative review, aspects that have the potential to add to the SIR model in the current literature are identified. By combining epidemiological findings with innovation theory, the paper contributes to a richer and more integrated understanding of the phenomena of diffusion of nanotechnological innovations. The motivation is to open a debate regarding the ability of the epidemiological model of SIR to reveal the impact of interventions affecting the diffusion of innovations.
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http://dx.doi.org/10.1016/j.heliyon.2025.e42309 | DOI Listing |
JMIR Public Health Surveill
September 2025
Department of Preventive Medicine, College of Medicine, Korea University, 73 Goryeodae-ro, Seoungbuk-gu, Seoul, 02841, Republic of Korea, 82 2-2286-1169.
Background: Scrub typhus (ST), also known as tsutsugamushi disease, is a common febrile vector-borne illness in South Korea, transmitted by trombiculid mites infected with Orientia tsutsugamushi, with rodents serving as the main hosts. Although vector-borne diseases like ST require both a One Health approach and a spatiotemporal perspective to fully understand their complex dynamics, previous studies have often lacked integrated analyses that simultaneously address disease dynamics, vectors, and environmental shifts.
Objective: We aimed to explore spatiotemporal trends, high-risk areas, and risk factors of ST by simultaneously incorporating host and environmental information.
Epidemiol Serv Saude
September 2025
Universidade Federal de Minas Gerais, Departamento de Farmácia Social, Belo Horizonte, MG, Brazil.
Objectives: To assess the persistence and time until discontinuation of biological drugs used by people with ankylosing spondylitis treated in the Brazilian Unified Health System and to investigate the factors associated with them.
Methods: Data were collected from an open historical cohort between 2018 and 2023 on the administrative processes required for requesting medicines from the specialized component of pharmaceutical assistance in Minas Gerais, Brazil. Sociodemographic and clinical data and treatment history were collected.
Ann Acad Med Singap
August 2025
Division of Medical Oncology, National Cancer Centre Singapore, Singapore.
Introduction: The high prevalence and mortality rates of breast cancer and lung cancer in Singapore necessitate robust screening programmes to enable early detection and intervention for improved patient outcomes, yet 2024 uptake and coverage remain suboptimal. This narrative review synthesises expert perspectives from a recent roundtable discussion and proposes strategies to advance breast cancer and lung cancer screening programmes.
Method: A 2024 roundtable convened clinical practitioners, health policymakers, researchers and patient advocates discussed current challenges and opportunities for improving cancer screening in Singapore.
Bull Math Biol
September 2025
Department of Mathematics, Siena University, 515 Loudon Road, Loudonville, NY, 12211, USA.
Autonomous differential equation compartmental models hold broad utility in epidemiology and public health. However, these models typically cannot account explicitly for myriad factors that affect the trajectory of infectious diseases, with seasonal variations in host behavior and environmental conditions as noteworthy examples. Fortunately, using non-autonomous differential equation compartmental models can mitigate some of these deficiencies, as the inclusion of time-varying parameters can account for temporally varying factors.
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September 2025
Department of Mathematics and Faculty of Medicine, The University of Ottawa, Ottawa, ON, K1N 6N5, Canada.
Host defense and pathogen virulence interact and mutually shape each other's evolution. Host-pathogen co-evolutionary outcomes have potentially significant impacts on population dynamics and vice versa. To investigate host-pathogen interactions and explore the impact of micro-level co-evolutionary outcomes on macro-level epidemics, we develop a co-evolutionary model with a combined host-defense strategy.
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