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http://dx.doi.org/10.12788/cutis.1162 | DOI Listing |
Melanoma Res
September 2025
Gynecological Oncology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS-CRO, National Cancer Institute Aviano, Aviano.
Peritoneal carcinomatosis represents an exceptionally rare metastatic pattern of cutaneous malignant melanoma, occurring in fewer than 1% of cases with distant spread and typically within the first few years after primary treatment. This report presents an unusual case with a markedly prolonged disease-free interval, clinically mimicking advanced ovarian carcinoma. We report the case of a 53-year-old woman treated more than 10 years ago for stage IIB nodular melanoma with surgery and adjuvant therapy.
View Article and Find Full Text PDFInt J Dermatol
September 2025
Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Introduction: Cutaneous scalp metastases from breast carcinoma (CMBC) represent an uncommon manifestation of metastatic disease, with heterogeneous clinical presentations, including nodular or infiltrative lesions and scarring alopecia (alopecia neoplastica). The absence of standardized diagnostic criteria, particularly for alopecic phenotypes, poses challenges to early recognition of CMBC, which may represent either the first indication of neoplastic progression or a late recurrence.
Materials And Methods: We retrospectively analyzed a multicenter cohort of 15 patients with histologically confirmed CMBC.
J Surg Case Rep
September 2025
Department of Dermatology and Sexually Transmitted Disease, Tishreen University Hospital, Lattakia 041, Syria.
Hepatoid adenocarcinoma of the lung (HAL) is a rare and aggressive subtype of pulmonary adenocarcinoma, with cutaneous metastasis being an uncommon clinical manifestation. A 49-year-old male presented with a painful, nodular skin lesion on the upper back. Histopathological examination confirmed it as a cutaneous metastasis of HAL.
View Article and Find Full Text PDFCureus
August 2025
Department of Ophthalmology, Hôpital Maisonneuve-Rosemont, Montreal, CAN.
Choroidal metastasis from occult cutaneous melanoma is rare and can masquerade as ocular inflammation. A 70‑year‑old man with sectoral anterior scleritis was found on multimodal imaging to have a solitary choroidal mass with mild periscleral fluid, prompting systemic evaluation that uncovered colonic polyps that, on histopathology, contained metastatic melanoma, a scalp primary, and widespread visceral, nodal, and intracranial metastases. Tumour cells stained HMB‑45, Melan‑A, and SOX10 positive, AE1/AE3 negative, and carried an NRAS‑Q61 mutation with wild‑type BRAF, confirming cutaneous origin.
View Article and Find Full Text PDFJ Am Acad Dermatol
September 2025
Division of Dermatology, Department of Medicine, Albert Einstein College of Medicine.