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Background: The variety of therapeutic associations in first-line treatment of advanced and metastatic renal cell cancer (mRCC) illustrates the complexity of toxicity management that can affect patients' health-related quality of life (HRQOL). Electronic monitoring applications have become part of the daily practice of providers in following up with people with cancer.
Objectives: This article offers perspectives for electronic patient-reported outcome measures (ePROMs) in clinical practice to enhance symptom management and HRQOL for patients with mRCC.
Methods: A narrative review combines the results of searches conducted on MEDLINE®, Embase®, and Cochrane Library for articles that identify therapeutic combinations used in treating mRCC, extract HRQOL data, and evaluate the benefits of ePROMs.
Findings: ePROMs can be adapted to the toxicity and symptom specificities encountered in patients with mRCC undergoing front-line treatment. Combined with multidimensional HRQOL indicators, these tools can improve symptom management and provide early support adapted to the patient's needs.
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http://dx.doi.org/10.1188/25.CJON.E17-E27 | DOI Listing |
Patient
September 2025
Patient Services, Anthony Nolan, 2 Heathgate Place, London, NW3 2NU, UK.
Background: There is increasing interest in using patient-reported outcome measures (PROMs) to assess quality of life (QoL) following hematopoietic cell transplant (HCT). However, there is limited consensus on how such data should be collected within HCT services. This survey study investigated health professionals (HCPs) views towards QoL data collection and factors affecting the use of PROMs within HCT centres in the UK.
View Article and Find Full Text PDFJ Orthop Sci
September 2025
American Hip Institute Research Foundation, Chicago, IL 60018, USA; American Hip Institute, Chicago, IL 60018, USA. Electronic address:
Background And Objective: With obese individuals experiencing osteoarthritis (OA) at early stages of life, hip resurfacing (HR) has emerged as an alternative to arthroplasty. The purpose is to conduct a short-term analysis on patients with obesity who underwent primary HR for OA compared to a benchmark control group of non-obese patients.
Materials And Methods: Patients with a body mass index (BMI) ≥ 30 kg/m2 who underwent HR from 2010 to 2021 were eligible for inclusion.
J Am Coll Cardiol
September 2025
Saint Luke's Mid America Heart Institute, Kansas City, Missouri, USA; University of Missouri-Kansas City's Healthcare Institute for Innovations in Quality, Kansas City, Missouri, USA.
Background: Clinical trials typically report average health status outcomes by treatment at single points in time, as opposed to participants' trajectories (or journeys) over time. Although ISCHEMIA (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches) demonstrated better mean health status at discrete times with an invasive treatment among those with baseline angina, the patterns of individual participants' angina over time are unknown.
Objectives: The purpose of this study was to identify patterns of individual participants' angina over time after invasive or conservative management strategies for chronic coronary disease.
J Arthroplasty
September 2025
Department of Orthopaedic Surgery, Washington University School of Medicine, Washington University in St Louis, St. Louis, Missouri, 63110, USA. Electronic address:
Introduction: Total hip arthroplasty (THA) with third-generation alumina ceramic heads on highly cross-linked polyethylene liners (HXLPE) has demonstrated excellent outcomes in young patients. However, concerns of ceramic head fracture, squeaking, stripe wear, and limited sizing led to the development of a fourth-generation ceramic head. The purpose of our study was to report on survivorship, wear characteristics, and patient-reported outcomes of THA with a fourth-generation 32-mm ceramic femoral head and HXLPE liner in patients 50 years or younger at 10-year minimum follow-up.
View Article and Find Full Text PDFJ Pain Symptom Manage
September 2025
Department of Palliative Medicine, OhioHealth Riverside Methodist Hospital, Columbus, Ohio (Beachy, Aung, Malone, Petros, Bertke); Department of Pharmacy, OhioHealth Riverside Methodist Hospital, Columbus, Ohio (Durell, Tressel).
Background: Opioids are widely used for pain management in hospitalized adults and can be administered through various routes. While oral (PO) and intravenous (IV) routes remain most common, the subcutaneous (SUB-Q) route is underutilized despite historical safety and supporting literature.
Objective: This quality improvement study implemented a revised standard of practice (SOP) for opioid administration, promoting the PO route when feasible and SUB-Q as the preferred parenteral route.