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Purpose: Total hip arthroplasty (THA) in patients with acetabular protrusion can be challenging due to the lack of acetabular bone support. Some patients may require a major reconstructive procedure to aid in the fixation of the acetabular components. The purpose of the study was to characterize the type of acetabular defects in patients with protrusion and to assess the need for major reconstruction.
Methods: This was a retrospective study of 125 THAs performed at a single tertiary center from 2010 to 2020 by a single surgeon in patients with acetabular protrusion. Demographics, operative details and radiographic details were recorded. THAs in which a structural graft, cage or augment were used for acetabular reconstruction were considered to have undergone a major reconstructive procedure and a classification system was proposed to identify patients requiring major reconstruction.
Results: 10 (8 %) THAs required a major reconstruction in our cohort (2- augment, 8- structural allograft. There was significant difference in acetabular defects based on the etiology. Major reconstruction was more common when the diagnosis was sequalae of tuberculosis or post-traumatic arthritis. Simple cavitatory defects seldom required a major reconstruction while combined defects and medial wall deficiency increased the risk of requiring a major reconstruction.
Conclusion: The severity of defects varied considerably with majority of patients having cavitatory type of defect which can be successfully managed without the need of any major reconstructive measures. A simple classification based on the type of defect and medial wall competency appeared to be useful in identifying patients who may need a major reconstructive procedure during THA.
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http://dx.doi.org/10.1016/j.jcot.2024.102847 | DOI Listing |
PLoS Negl Trop Dis
September 2025
Department of Clinical Science, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Background: Salmonella enterica encompasses over 2,600 serovars, including several commonly associated with severe infection in humans. Salmonella is a major cause of sepsis in Africa; however, diagnosis requires clinical microbiology facilities. Environmental surveillance has the potential to play a role in Salmonella surveillance.
View Article and Find Full Text PDFBioinformatics
September 2025
Institute of Ecology and Evolution, University of Edinburgh, Edinburgh, United Kingdom.
Summary: In Bayesian phylogenetic and phylodynamic studies it is common to summarise the posterior distribution of trees with a time-calibrated summary phylogeny. While the maximum clade credibility (MCC) tree is often used for this purpose, we here show that a novel summary tree method-the highest independent posterior subtree reconstruction, or HIPSTR-contains consistently higher supported clades over MCC. We also provide faster computational routines for estimating both summary trees in an updated version of TreeAnnotator X, an open-source software program that summarizes the information from a sample of trees and returns many helpful statistics such as individual clade credibilities contained in the summary tree.
View Article and Find Full Text PDFHernia
September 2025
Center for Perioperative Optimization, Department of Surgery, Copenhagen University Hospital - Herlev and Gentofte, Borgmester Ib Juuls Vej 1, Herlev, DK-2730, Denmark.
Purpose: Primary ventral hernia repair is a common elective procedure; however, mesh placement practices vary widely, and there is limited evidence to guide optimal placement. This international study examined surgeons' preferences and considerations regarding mesh placement in elective primary ventral hernia repair.
Methods: We conducted an international cross-sectional survey targeting surgeons experienced in primary ventral hernia repair.
Zool Res
September 2025
Institute of Entomology, College of Life Sciences, Nankai University, Tianjin 300071, China. E-mail:
The collision of the Indian and Eurasian plates during the Eocene represents a major tectonic shift that significantly altered biotic dynamics and promoted species diversification across the Oriental region. To explain the diversification of taxa from the Indian subcontinent into Southeast Asia, two principal hypotheses have been proposed: the "Biotic-ferry" and "Step-stone" models. The subfamily Perittopinae, a lineage of semi-aquatic bugs comprising a single genus and 20 extant species, provides an ideal system for testing these hypotheses due to its disjunct distribution spanning the Indian subcontinent and Southeast Asia.
View Article and Find Full Text PDFInt J Numer Method Biomed Eng
September 2025
Joint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran.
The need for total knee arthroplasty (TKA) has grown significantly in recent years. The cutting angle in TKA plays a major role in the functionality and life expectancy of the knee implant components. This study aims to personalize the femur bone cutting angle selection for implant placement.
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