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http://dx.doi.org/10.1183/13993003.02170-2024 | DOI Listing |
Probiotics Antimicrob Proteins
September 2025
Operational Research Centre in Healthcare, Near East University, Nicosia, Cyprus.
Probiotics are live beneficial microorganisms that confer health benefits to the host when administered in adequate amounts, have gained considerable scientific and commercial interest for their ability to support gut health, strengthen immunity, and reduce disease risk. This review traces the genesis of probiotic science from its origins in traditional fermented foods to contemporary clinical applications, offering a conceptual understanding of its evolution. A clear distinction is drawn between endogenous probiotics, naturally resident in the human microbiome, and exogenous probiotics, introduced via dietary supplements and functional foods.
View Article and Find Full Text PDFBiol Lett
September 2025
Department of Vertebrate Zoology, Division of Mammals, Smithsonian National Museum of Natural History, Washington, DC, USA.
Accurately identifying evolutionarily significant units (ESUs) is crucial for conservation planning, especially for species like pangolins threatened by overhunting and habitat loss. ESUs help categorize different pangolin populations, aiding in understanding their genetic diversity and distribution, which is vital for targeted conservation efforts. This research generated mitochondrial genomes from historical museum specimens of Sunda pangolins () from underrepresented locations, uncovering a new evolutionary lineage from the Mentawai Islands that diverged from Indochina and west Sundaland populations around 760 000 years ago.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
September 2025
Department of Biochemical Pathophysiology, Medical Research Laboratory, Institute of Integrated Research, Institute of Science Tokyo, Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.
Adrenal lipomas are benign tumors containing ectopic adipose tissue in the adrenal gland, an organ that normally lacks both adipocytes and their progenitors. The origin of this ectopic fat remains enigmatic, and the absence of a genetic animal model has hindered its investigation. Phosphatidylinositol 3,4,5-trisphosphate [PI(3,4,5)P], a key signaling lipid that regulates cellular growth and differentiation, is tightly regulated by the lipid phosphatases PTEN (phosphatase and tensin homolog) and SHIP2 (SH2-containing inositol phosphatase 2).
View Article and Find Full Text PDFAllergol Immunopathol (Madr)
September 2025
Department of Respiratory Disease, Children's Hospital Affiliated to Shandong University, Jinan, China.
Background: Asthma is a chronic respiratory disease with complex pathogenesis. Some studies suggest that certain trace metals may be associated with asthma. However, the relationship between serum copper (Cu) and childhood asthma remains unclear.
View Article and Find Full Text PDFFood Res Int
November 2025
Department of Veterinary Medicine, University of Sassari, Via Vienna 2, 07100 Sassari, Italy. Electronic address:
Fish is one of the most common causes of food allergy. The global prevalence of fish allergy has increased over the years as a result of the increased fish consumption. In allergic individuals even small amounts of allergen can trigger a life-threatening allergic reaction.
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