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Purpose: To investigate the accuracy of proton density fat fraction (PDFF) measurement using chemical shift-encoded MRI (CSE-MRI) with fast imaging techniques in a phantom.
Methods: A 1.5T imaging system (Prodiva; Philips Healthcare) and PDFF phantom (Fat Fraction Phantom Model 300; Calimetrix) were used in this study. The acquisitions without fast imaging techniques (conventional acquisition), with parallel imaging in phase-encode direction (SENSE acquisition), with compressed sensing (CS-SENSE acquisition), and with parallel imaging in both phase-encode and slice-encode direction (Dual-SENSE acquisition) were performed. The following acceleration factors in SENSE and CS-SENSE acquisition were used: 2.0, 3.0, 4.0, 5.0, 6.0, 7.0, and 8.0. For Dual-SENSE acquisition, the same acceleration factors (1.5, 2.0, 3.0, 4.0, 5.0) were set in each of the two directions. The relationships between reference PDFF values and PDFF measurements obtained using each acquisition were assessed using linear regression analysis and Bland-Altman analysis.
Results: According to the linear regression analysis, the slopes and intercepts of regression lines were from 0.87 to 1.02 and from 0.06% to 3.55%, respectively. According to Bland-Altman analysis, there were fixed bias between reference PDFF values and PDFF measurements obtained using SENSE acquisition with reduction factor 8.0 and Dual-SENSE acquisition with reduction factor 5.0. For CS-SENSE acquisition with reduction factor from 7.0 to 8.0, SENSE acquisition with reduction factor from 3.0 to 8.0, and Dual-SENSE acquisition with reduction factor from 2.0 to 5.0, some vials had ±1.5% or more errors between the reference PDFF values and PDFF measurements in the range of 0% to 50% PDFF.
Conclusion: In CS-SENSE acquisition, the accuracy of PDFF measurement was maintained within 1.5% up to a reduction factor 6.0. The accuracy of PDFF measurement was maintained within 1.5% up to a reduction factor 2.0 in SENSE acquisition and a reduction factor 1.5 in Dual-SENSE acquisition.
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http://dx.doi.org/10.6009/jjrt.25-1464 | DOI Listing |
Waste Manag Res
September 2025
School of Environmental Science and Engineering, Tongji University, Shanghai, PR China.
Waste three-way catalysts (TWCs) and waste LiCoO batteries represent critical environmental challenges due to hazardous components yet contain high-value resources, and their recycling has garnered widespread attention. We propose a novel 'waste-to-waste' synergistic recycling where spent LiCoO batteries reconstruct mineral phases of waste TWCs, enabling co-recovery of platinum group metals and Li/Co without traditional oxidants. However, the environmental performance of this process still requires further analysis.
View Article and Find Full Text PDFF1000Res
September 2025
School of Management, University of Khartoum, Khartoum, Khartoum, Sudan.
Background: At the 2020 UN General Assembly, China pledged to peak carbon emissions before 2030 and achieve carbon neutrality by 2060. However, the traditional social development model has led to increasing carbon emissions annually, highlighting the need to resolve the contradiction between development and carbon reduction. This study examines the relationship between carbon emissions, economy, population, and energy consumption in a specific region to support carbon peak and neutrality goals.
View Article and Find Full Text PDFPeriodontol 2000
September 2025
Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.
This systematic review and meta-analysis aimed to evaluate the long-term clinical outcomes of regenerative procedures compared with access flap surgery for the treatment of intrabony defects, with a minimum follow-up period of 5 years. A systematic review protocol following PRISMA guidelines was conducted. Both electronic and manual searches were conducted to identify randomized clinical trials (RCTs) on regenerative treatment of deep intrabony defects (≥3 mm) with a follow-up of at least 5 years.
View Article and Find Full Text PDFMol Ther
September 2025
Center of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China; Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China. Electronic address:
The reduction of TCF-1 during CD8 T cell exhaustion leads to attenuated antitumor activity and diminished responsiveness to immune checkpoint inhibitors. However, how TCF-1 is downregulated remains unclear. Here, we showed that during CD8 T cell exhaustion, lnc-SUMF2-8, induced by transcription factor TOX, can bind to cytosolic TCF-1, and direct it to the lysosome for degradation.
View Article and Find Full Text PDFJDR Clin Trans Res
September 2025
School of Dentistry, Faculty of Health and Behavioural Sciences, The University of Queensland, Brisbane, Queensland, Australia.
Objectives: Socioeconomic status (SES) has a significant effect on the burden of early childhood caries (ECC), yet addressing SES disparities remains challenging. This study aimed to identify and quantify the most impactful mediator linking SES effect to the occurrence of ECC using advanced causal mediation analysis, to inform targeted interventions that reduce SES-related disparities in ECC.
Methods: Data were drawn from the Study of Mothers' and Infants' Life Events, a cohort of 2,182 mother-child dyads recruited from Adelaide's 3 largest public hospitals (2013-2014).