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Prior studies report a decline in male twin live births during economically stressful periods, presumably owing to higher selection against frail male gestations, yet no study has examined the natural corollary: whether provision of economic support increases rates of male twin births. We examined whether male twin live births increase following income gains from the Alaska Permanent Fund Dividend (PFD)-the longest running unconditional cash transfer program in the US. We obtained the monthly volume of male (and female) twin and singleton live births, from January 1980 to December 2019, from Alaska's Department of Health. Data on PFD timing and payment amounts came from Alaska's Department of Revenue. We used time-series analyses to gauge whether the odds of male twin live births increase within 2-6 months following PFD receipt, controlling for autocorrelation. Results suggest that for every $1000 increase in PFD payments, the odds of male twin live births increase by 0.002 ( < .05) three months following PFD disbursement. This corresponds with 50 additional (individual) male twin live births statistically attributable to the cumulative PFD amount disbursed over our study period. Income gains through the PFD may correspond with reduced male-specific selection in Alaska.
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http://dx.doi.org/10.1017/thg.2024.50 | DOI Listing |
BMJ Open
September 2025
Department of Twin Research and Genetic Epidemiology, King's College London, London, UK
Objectives: To estimate the association between socioeconomic background (derived from household main earner occupation when the survey respondent was aged 14 years old) and likelihood of working as a doctor in adulthood in the UK, and estimate how associations varied over time for respondents who turned 18 years old in different decades.
Design: Observational study of 10 years of pooled data from a nationally representative government survey.
Setting: The United Kingdom (UK).
Invest Ophthalmol Vis Sci
September 2025
The University of Leicester Ulverscroft Eye Unit, School of Psychology and Vision Sciences, University of Leicester, Leicester, United Kingdom.
Purpose: To define the genetic architecture of foveal morphology and explore its relevance to foveal hypoplasia (FH), a hallmark of developmental macular disorders.
Methods: We applied deep-learning algorithms to quantify foveal pit depth from central optical coherence tomography (OCT) B-scans in 61,269 UK Biobank participants. A genome-wide association study (GWAS) was conducted using REGENIE, adjusting for age, sex, height, and ancestry.
Am J Primatol
September 2025
Department of Genetics and Genome Biology, University of Leicester, Leicester, UK.
Goeldi's monkey (Callimico goeldii, the lone species in this genus) shows an array of characteristics that are typical for both New World primate families, the Cebidae and the Callitrichidae, and as such their taxonomic classification has remained in question. Based on DNA, the genus Callimico is regarded as a member of the monophyletic group of clawed New World monkeys (Callitrichidae). Callitrichids, as a rule, give birth to twins, which are blood chimeras due to placental blood vessel anastomoses.
View Article and Find Full Text PDFCureus
August 2025
Pediatric Nephrology, Hospital Pediátrico, Unidade Local de Saúde de Coimbra, Coimbra, PRT.
Introduction Nephrogenic diabetes insipidus (NDI) is a rare condition caused by renal resistance to the action of antidiuretic hormone (ADH) at the level of the distal tubule, resulting in impaired urinary concentration and consequent polyuria. NDI may be hereditary, most commonly X-linked due to AVPR2 gene mutations, or acquired. Objective To characterize the clinical features, management strategies, and outcomes of patients with NDI followed at a tertiary pediatric nephrology center.
View Article and Find Full Text PDFJMIR Res Protoc
September 2025
Division of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, Medical School, University of Minnesota-Twin Cities, Minneapolis, MN, United States.
Background: Approximately 69% of Americans with spinal cord injury (SCI) have neuropathic pain. Research suggests that impairments in mental body representations (MBRs; ie, representations of the body in the brain) likely contribute to neuropathic pain. Clinical trials in adults with SCI, focused on restoring MBR, led to improvements in sensation and movement as well as neuropathic pain relief.
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