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http://dx.doi.org/10.1021/acs.jafc.5c00651 | DOI Listing |
Signal Transduct Target Ther
August 2025
Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea.
Hemoglobin (Hb) is well known for transporting oxygen in the blood, but its role in the brain remains poorly understood. Here, we identified Hb in the cytosol, mitochondria, and nuclei of hippocampal and substantia nigra astrocytes and dopaminergic neurons. As a pseudoperoxidase, Hb decomposes hydrogen peroxide (HO) and mitigates HO-induced oxidative damage.
View Article and Find Full Text PDFPast research on tolerance has often focused on tolerance toward specific political or social groups. In the present research, we introduce a general tolerant attitude measure tapping tolerant attitudes toward dissenting others which can be used in wide variety of contexts. Moreover, we investigated for which individuals it is easier to have a tolerant attitude and compared different entitlement beliefs (the perception of having the same (i.
View Article and Find Full Text PDFNat Med
August 2025
David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Investments in women and their health hold transformative potential, serving as powerful drivers of gender equality, poverty reduction, equity and economic development. However, current investments are both insufficient and inappropriately designed to address the complex health needs of women throughout the life course. This paper explores the intrinsic returns that would stem from a virtuous cycle of investment in the health of women-by allowing full access to education and fair labor-force participation-as well as the instrumental returns to economic growth and sustainability.
View Article and Find Full Text PDFNature
August 2025
Toulouse School of Economics, CNRS (TSM-R), University of Toulouse-Capitole, Toulouse, France.
Predicting the social and behavioural impact of future technologies before they are achieved would enable us to guide their development and regulation before these impacts get entrenched. Traditionally, this prediction has relied on qualitative, narrative methods. Here we describe a method that uses experimental methods to simulate future technologies and collect quantitative measures of the attitudes and behaviours of participants assigned to controlled variations of the future.
View Article and Find Full Text PDFBiomedicines
June 2025
Respiratory and Allergy Clinic, IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
: Severe asthma is a respiratory condition, involving treatments (i.e., inhaled steroids, systemic steroids, hospitalization) capable of increasing significant carbon footprint, raising concerns about environmental sustainability in healthcare.
View Article and Find Full Text PDF