98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1001/jamapediatrics.2024.6557 | DOI Listing |
J Oncol Pharm Pract
September 2025
Department of Research & Development, Squad Medicine and Research (SMR), Amadalavalasa, Andhra Pradesh, India.
Cancer vaccines represent a transformative shift in oncology, aiming to prevent malignancies or treat established cancers by training the immune system to recognize tumor-specific or tumor-associated antigens. This review explores the diverse platforms and mechanisms supporting cancer vaccines, ranging from prophylactic vaccines such as HPV and hepatitis B vaccines that have significantly reduced virus-related cancers to therapeutic vaccines like Sipuleucel-T and T-VEC that extend survival in prostate cancer and melanoma. Vaccine types are classified, and delivery platforms including mRNA, peptide, dendritic cell and viral vector-based approaches are examined alongside pivotal clinical trial outcomes.
View Article and Find Full Text PDFNeuropsychiatr Dis Treat
August 2025
Department of Psychiatry and Behavioral Sciences, New York Medical College, Valhalla, New York, USA.
Brexpiprazole is a second-generation antipsychotic with multiple indications, including the treatment of schizophrenia. As a partial dopamine agonist, brexpiprazole differs from most other antipsychotics, yet uncertainties about its full mechanism of action have led to some ambiguity among prescribers. To address this gap, an international panel of psychiatric experts was organized and convened with funding from Otsuka Pharmaceutical Europe Ltd and H.
View Article and Find Full Text PDFBMJ Public Health
August 2025
Flinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.
Objectives: There are large and growing communities of Chinese, Vietnamese and Arab populations within many high-income countries, including Australia. These populations experience disproportionately higher rates of tobacco smoking. Cessation strategies are required that acknowledge the cultural factors shaping smoking behaviours.
View Article and Find Full Text PDFBMJ Public Health
August 2025
Health and Society Group, Social Science Department, Wageningen University & Research, Wageningen, Gelderland, The Netherlands.
Introduction: Improving health, in particular of people in a disadvantaged socioeconomic position (SEP), requires multilevel health promotion programmes with community engagement. However, the impacts of such complex and challenging programmes are not yet clear. This study aims to show the impact of a participatory multilevel family health promotion programme in a low-income neighbourhood at intrapersonal, interpersonal, organisational, community and policy level.
View Article and Find Full Text PDFCureus
August 2025
General Surgery, Lahore General Hospital, Lahore, PAK.
Urinary bladder cancer contributes significantly to the global cancer burden and is more prevalent in the developed world. We present the case of a 54-year-old male smoker who underwent transurethral resection of bladder tumor and consequent trimodality therapy (induction chemotherapy followed by concomitant chemo-radiotherapy). His disease was staged at cT3N0M0.
View Article and Find Full Text PDF