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Aims: To verify the possible association between the stomatognathic and the visual system by analyzing the effects that different mandibular postures may have on the accommodative capacity and ocular convergence and by assessing whether temporomandibular disorders (TMD) can influence visual abilities.
Materials And Methods: A case-control study was performed during a 1-year period on a sample of 100 subjects (50 cases and 50 controls). The subjects underwent a gnathological examination, and two visual tests were performed in three different jaw positions: maximum intercuspation, resting position, and open mouth. The statistical analyses were performed using the software SPSS program based on test to compare the different jaw positions and the odds ratio to understand the prevalence of visual defects in TMD patients.
Results: A statistically significant worsening was observed comparing the visual capacities measurements from the maximum intercuspation to the open mouth position; "case group" measurements showed a worsening trend compared to the "control group" ( value < 0.05 in all comparisons). Furthermore, the examinations showed statistically significant results with reference to the relationship between TMD and their negative influence on visual abilities ( value = 0.007 for convergence and value = 0.012 for accommodation).
Conclusions: Based on our data, TMD individuals performed worse in vision tests compared to healthy subjects and the presence of occlusal contacts appears to improve convergence and accommodation. The reduced reproducibility and accuracy of the orthoptic tests and the small sample number were the principal limitations of our study. The future perspective could be to investigate whether the visual apparatus could benefit from the treatment of stomatognathic disorders.
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http://dx.doi.org/10.4103/jispcd.jispcd_191_23 | DOI Listing |
Cereb Cortex
August 2025
Nencki Institute of Experimental Biology, PAS, 3 Pasteur Street, 02-093 Warsaw, Poland.
In the visual cortices, receptive fields (RFs) are arranged in a gradient from small sizes in the center of the visual field to the largest sizes at the periphery. Using functional magnetic resonance imaging (fMRI) mapping of population RFs, we investigated RF adaptation in V1, V2, and V3 in patients after long-term photoreceptor degeneration affecting the central (Stargardt disease [STGD]) and peripheral (Retinitis Pigmentosa [RP]) regions of the retina. In controls, we temporarily limited the visual field to the central 10° to model peripheral loss.
View Article and Find Full Text PDFPatient
September 2025
PPD Evidera Patient-Centered Research, Thermo Fisher Scientific, Waltham, MA, USA.
Background: Migraine care is often suboptimal owing to undertreatment, variation in clinical outcomes and administration methods among existing treatments, and between- and within-individual heterogeneity in the clinical course of migraine. In response to these challenges, preference studies have been increasingly conducted to inform treatment decision-making and development. However, gaps remain in understanding how treatment preferences have been assessed across different migraine studies.
View Article and Find Full Text PDFTissue Eng Regen Med
September 2025
Department of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, #505 BanPo-Dong, SeoCho-Gu, Seoul, 06591, Republic of Korea.
Background: Sjögren's syndrome (SS) is a chronic autoimmune disease delineated by excessive lymphocyte infiltration to the lacrimal or salivary glands, leading to dry eye and dry mouth. Exosomes secreted from mesenchymal stem cells (MSC) are known to have anti-inflammatory and tissue regeneration abilities. This study endeavored to demonstrate the effect of MSC-derived exosomes on the clinical parameter of dry eyes and associated pathology in SS mouse model.
View Article and Find Full Text PDFInt J Comput Assist Radiol Surg
September 2025
Institute of Computer Science, Friedrich-Schiller-Universität, Fürstengraben 1, 07743, Jena, Thuringia, Germany.
Purpose: Cerebral aneurysms are blood-filled bulges that form at weak points in blood vessel walls, and their rupture can lead to life-threatening consequences. Given the high risk associated with these aneurysms, thorough examination and analysis are essential for determining appropriate treatment. While existing tools such as ANEULYSIS and its web-based counterpart WEBANEULYSIS provide interactive means for analyzing simulated aneurysm data, they lack support for collaborative analysis, which is crucial for enhancing interpretation and improving treatment decisions in medical team meetings.
View Article and Find Full Text PDFJ Neurooncol
September 2025
Department of Radiology, The Affiliated Hospital of Qingdao University, Qingdao, 266003, Shandong, China.
Rationale And Objectives: Double expression lymphoma (DEL) is an independent high-risk prognostic factor for primary CNS lymphoma (PCNSL), and its diagnosis currently relies on invasive methods. This study first integrates radiomics and habitat radiomics features to enhance preoperative DEL status prediction models via intratumoral heterogeneity analysis.
Materials And Methods: Clinical, pathological, and MRI imaging data of 139 PCNSL patients from two independent centers were collected.