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http://dx.doi.org/10.2337/dc24-2322 | DOI Listing |
Turk J Pediatr
September 2025
Division of Pediatric Rheumatology, Department of Pediatrics, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, İstanbul, Türkiye.
Background: We aimed to document childhood onset mevalonate kinase deficiency (MKD) and to explore treatment responses and diagnostic challenges in regions endemic to familial Mediterranean fever (FMF).
Methods: This retrospective study included patients under 18 years of age, diagnosed with MKD and followed for at least six months at the pediatric rheumatology department of Istanbul University - Cerrahpaşa Medical Faculty between 2016 and 2024.
Results: Of 33 patients, 51.
Ocular relapse in pediatric acute lymphoblastic leukemia (ALL) is rare and typically associated with central nervous system or bone marrow involvement. Anterior segment infiltration as the sole manifestation of relapse is exceptionally uncommon and may mimic noninfectious uveitis, leading to diagnostic delay. We report the case of a 4-year-old boy with a history of B-cell precursor ALL, diagnosed at age 2 and treated according to the ALL IC BFM 2009 protocol.
View Article and Find Full Text PDFIndian Dermatol Online J
September 2025
Department of Pathology, All India Institute of Medical Sciences, Patna, Bihar, India.
JACC Case Rep
September 2025
Division of Academic Affairs and Research, Orlando Regional Medical Center, Orlando, Florida, USA. Electronic address:
Background: Tachycardia-induced cardiomyopathy (TICM) is typically reversible with rhythm control, but individual susceptibility remains poorly understood and may reflect genetic predisposition.
Case Summary: A 66-year-old woman with paroxysmal atrial fibrillation (AF) presented with new-onset heart failure. Genetic testing identified a likely pathogenic heterozygous ABCC9 gene variant (c.
Avian Pathol
September 2025
Department of Animal Medicine, Production and Health (MAPS), University of Padua, Legnaro (PD), Italy.
Infectious bursal disease virus (IBDV) is a highly contagious, economically relevant immunosuppressive pathogen of chickens. Despite belonging to a single serotype, virulent IBDVs display a remarkable heterogeneity in genetic and functional features. Traditionally, strains are categorized into classical, variant and very virulent viruses, but many atypical IBDVs have been recently identified.
View Article and Find Full Text PDF