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Rationale & Objective: Remote patient monitoring (RPM) could improve the quality and efficiency of acute kidney injury (AKI) survivor care. This study described our experience with AKI RPM and characterized its effectiveness.
Study Design: A cohort study matched 1:3 to historical controls.
Setting & Participants: Patients hospitalized with an episode of AKI who were discharged home and were not treated with dialysis.
Exposure: Participation in an AKI RPM program, which included use of a home vital sign and symptom monitoring technology and weekly in-center laboratory assessments.
Outcomes: Risk of unplanned hospital readmission or emergency department (ED) visit within 6 months.
Analytic Approach: Endpoints were assessed using Cox proportional hazards models.
Results: Forty of the 49 patients enrolled in AKI RPM (82%) participated in the program after hospital discharge. Seventy three percent of patients experienced one AKI RPM alert, most commonly related to fluid status. Among those with stage 3 AKI, the risk of unplanned readmission or ED visit within 6 months of discharge was not different between AKI RPM patients (n = 34) and matched controls (n = 102) (HR 1.33 [95% CI, 0.81-2.18]; = 0.27). The incidence of an ED visit without hospitalization was significantly higher in the AKI RPM group (HR 1.95, [95% CI, 1.05-3.62]; = 0.035). The risk of an unplanned readmission or ED visit was higher in those with baseline eGFR < 45 mL/min/1.73 m exposed to AKI RPM (HR 2.24 [95% CI, 1.19-4.20]; = 0.012) when compared with those with baseline eGFR ≥45 mL/min/1.73 m (HR 0.69 [95% CI, 0.29-1.67]; = 0.41) (test of interaction = 0.04).
Limitations: Small sample size that may have been underpowered for the effectiveness endpoints.
Conclusions: AKI RPM, when used after hospital discharge, led to alerts and interventions directed at optimizing kidney health and AKI complications but did not reduce the risk for rehospitalization.
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http://dx.doi.org/10.1016/j.xkme.2024.100905 | DOI Listing |
ASAIO J
May 2025
From the Division of Cardiothoracic Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin.
Venopulmonary arterial (VPA) extracorporeal membrane oxygenation (ECMO) is emerging as an alternative to traditional venovenous (VV) ECMO for respiratory failure. This study compares rates of hemolysis and acute kidney injury (AKI) between VPA and VV ECMO. We retrospectively analyzed 142 patients (VPA: n = 84, VV: n = 58) who underwent ECMO from 2019 to 2023.
View Article and Find Full Text PDFKidney Med
November 2024
Department of Pharmacy, Mayo Clinic, Rochester, MN.
Rationale & Objective: Remote patient monitoring (RPM) could improve the quality and efficiency of acute kidney injury (AKI) survivor care. This study described our experience with AKI RPM and characterized its effectiveness.
Study Design: A cohort study matched 1:3 to historical controls.
Open Forum Infect Dis
November 2023
Clinical Pharmacy Services, VA St Louis Health Care System, St. Louis, Missouri, USA.
Background: Data is limited comparing oritavancin (ORT) to the standard-of-care (SOC) for the treatment gram-positive blood stream infections (BSI).
Methods: This was a retrospective study of all patients in the Veteran's Affairs Health Care System treated with at least 1 dose of oritavancin or at least 5 days of vancomycin, daptomycin, ceftaroline, ampicillin, ampicillin-sulbactam, nafcillin, oxacillin, or cefazolin for a documented gram-positive BSI from 1 January 2015 to 30 June 2021. Patients with polymicrobial blood cultures or positive cultures from other sites were included if the organisms were sensitive to the incident antimicrobial; no concomitant antimicrobials could be used once the incident agent was started.
Mayo Clin Proc Digit Health
December 2023
Department of Medicine, Mayo Clinic, Rochester, MN.
Objective: To describe the creation of a scalable framework for a Remote Patient Monitoring (RPM) program tied to a large medical practice.
Patients And Methods: In July 2020, at Mayo Clinic Rochester, we initiated the process to combine human-centered design, health systems engineering, and clinical expertise to develop and refine RPM programs and explore new medical conditions where RPM could be beneficial. We report on the creation of the overarching RPM program, the development of a hybrid nursing model, the technology used for each population, and the lessons learned throughout the process.
Can J Kidney Health Dis
August 2023
Division of Nephrology & Hypertension, Mayo Clinic, Rochester, MN, USA.
Unlabelled: Acute kidney injury (AKI) survivors have a dynamic posthospital course which warrants close monitoring. Remote patient monitoring (RPM) could be used to improve quality and efficiency of AKI survivor care.
Objective: The objective of this report was to describe the development and preliminary feasibility of an AKI RPM program launched in October 2021.