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Previous research has shown that students employ intuitive thinking when understanding scientific concepts. Three types of intuitive thinking-essentialist, teleological, and anthropic thinking-are used in biology learning and can lead to misconceptions. However, it is unknown how commonly these types of intuitive thinking, or cognitive construals, are used spontaneously in students' explanations across biological concepts and whether this usage is related to endorsement of construal-consistent misconceptions. In this study, we examined how frequently undergraduate students across two U.S. universities ( = 807) used construal-consistent language (CCL) to explain in response to open-ended questions related to five core biology concepts (e.g., evolution), how CCL use differed by concept, and how this usage was related to misconceptions agreement. We found that the majority of students used some kind of CCL in the responses to these open-ended questions and that CCL use varied by target concept. We also found that students who used CCL in their response agreed more strongly with misconception statements, a relationship driven by anthropocentric language use, or language that focused on humans. These findings suggest that American university students use intuitive thinking when reasoning about biological concepts with implications for their understanding.
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http://dx.doi.org/10.1187/cbe.24-07-0198 | DOI Listing |
Microsc Res Tech
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Department of River Ecology, Helmholtz Centre for Environmental Research-UFZ, Magdeburg, Germany.
This review is intended as a guideline for beginners in confocal laser scanning microscopy. It combines basic theoretical concepts, such as fluorescence principles, resolution limits, and imaging parameters with practical guidance on sample preparation, staining strategies, and data acquisition using confocal microscopy. The aim is to combine technical and methodological aspects in order to provide a comprehensive and accessible introduction.
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RCSB Protein Data Bank, Institute for Quantitative Biomedicine, Rutgers University, Piscataway, New Jersey, United States.
Structure-function relationships are a core concept in many STEM disciplines. Most biology curricula introduce students to macromolecules, their building blocks, and other small molecules that play key roles in biological processes. However, the shapes, interactions, and functions of these molecules are often discussed using schematic diagrams, ignoring the vast amounts of three-dimensional structural and bioinformatics data freely available from public data resources.
View Article and Find Full Text PDFChem Sci
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Molecular AI, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca Gothenburg Sweden
Incorporating non-natural amino acids (NNAAs) into peptides enhances therapeutic properties, including binding affinity, metabolic stability, and half-life time. The pursuit of novel NNAAs for improved peptide designs faces the challenge of effective synthesis of these building blocks as well as the entire peptide itself. Solid-Phase Peptide Synthesis (SPPS) is an essential technology for the automated assembly of peptides with NNAAs, necessitating careful protection for effective coupling of amino acids in the peptide chain.
View Article and Find Full Text PDFPatterns (N Y)
July 2025
Department for Physics and Astronomy, Kirchhoff Institute for Physics, Heidelberg University, Baden-Württemberg, 69120 Heidelberg, Germany.
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View Article and Find Full Text PDFCancer Biol Med
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Yan'an Key Laboratory of Microbial Drug Innovation and Transformation, Yan'an Medical School of Yan'an University, Yan'an 716000, China.
The occurrence and progression of liver cancer are closely associated with mitochondrial dysfunction. Mitochondria exhibit characteristics, such as decreased oxidative phosphorylation efficiency, abnormal accumulation of reactive oxygen species in liver cancer and promoting tumor proliferation and drug resistance through the Warburg effect, as the core of energy metabolism and apoptosis regulation. Mutations in mitochondrial DNA (mtDNA) and dysregulation of mitochondrial autophagy (mitophagy) further enhance the invasive and metastatic capabilities of liver cancer.
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