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Rationale: Developing a feasible and sensitive evaluation strategy for a new mental health service is a challenge that requires consideration of what a service is trying to achieve and what a 'good' outcome might look like. Perinatal mental illnesses are complex in their causes and treatment. Mother Baby Units provide specialist perinatal mental health care to parents experiencing mental illness in the perinatal period, with evaluations demonstrating clinical and social outcomes. There has however been remarkably little research on how MBUs achieve these outcomes.
Method: This paper outlines the process and components of designing an evaluation plan for a new perinatal mental health unit, summarising outcome measures considered and the methodology of the evaluation strategy.
Results: A meaningful realist approach was designed. This innovative dualistic methodology is intended to develop theories of what might cause change while also considering what components of interventions parents experience as meaningful.
Conclusion: Articulating the approach to evaluation provides a contribution to evaluation knowledge for others evaluating complex public health interventions. The relational nature of perinatal mental health experiences challenges individualistic approaches to care delivery, funding and evaluation. As part of service establishment, there is a need to consider what a 'good' outcome of care might be and to develop evaluation approaches that capture the relational components of recovery as well as the factors that support families to sustain change.
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http://dx.doi.org/10.1111/jep.14269 | DOI Listing |
Asian J Psychiatr
August 2025
Department of Psychiatry, Kakogawa Central City Hospital, Hyogo, Japan. Electronic address:
Soc Psychiatry Psychiatr Epidemiol
September 2025
Centre for Global Mental Health, Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Purpose: Understanding the mechanisms through which poverty influences perinatal depression can provide insight into how to develop interventions to improve maternal mental health. To address this question, we aim to estimate indirect effects of important mediators on the causal relationship between food insecurity and symptoms of postnatal depression.
Methods: We used data from the control arm of the Africa Focus on Intervention Research for Mental health - South Africa (AFFIRM-SA) trial that included pregnant women with perinatal depression.
Biol Psychiatry
September 2025
Department of Psychiatry, University of Iowa, Iowa City, IA 52242; Iowa Neurosciences Institute, University of Iowa, Iowa City, IA 52242; Department of Obstetrics and Gynecology, University of Iowa, Iowa City, IA 52242. Electronic address:
Perinatal mood and anxiety disorders (PMADs) are a spectrum of mental health conditions that are the most common pregnancy-related complications in the United States. Despite great strides in developing appropriate pharmacological and psychological treatments, PMADs continue to lack biological measures for diagnosis and prediction. Such measures could be effectively utilized to subtype and mechanistically explore PMADs and appropriately leverage mental healthcare resources.
View Article and Find Full Text PDFJ Affect Disord
September 2025
PROMENTA Research Center, Department of Psychology, University of Oslo, Norway; PsychGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway.
Background: While genetic factors are important influences on maternal mental health, few studies have used symptom-level analyses to examine how genetic liability is related to the experience of specific mental health problems in mothers. A symptom-level approach can account for disorder heterogeneity and delineate key associations between genetic liabilities and mental health.
Methods: Three waves of data (30 weeks of gestation, 6 and 18 months postpartum) from the Norwegian Mother, Father and Child Cohort Study (MoBa) were used to assess item-level associations between genetic liabilities to depression, anxiety, neuroticism and positive affect, and maternal mental health phenotypes (i.