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Article Abstract
Himalaflavones F () and G (), two new flavonoids, along with eight known ones ()were isolated from the roots of Edgew. The chemical structures of these compounds were elucidated by 1D/2D NMR, UV and HR-ESI-ME data. Meanwhile, the anti-inflammatory activities of all isolates were test by using Griess method. Among them 10 μM of compounds , , and could decrease the NO release against LPS-induced RAW264.7 macrophages. The results suggested that these compounds have the potential to be developed as anti-inflammatory drugs.
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| http://dx.doi.org/10.1080/14786419.2024.2446705 | DOI Listing |
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Himalaflavones F and G, two new flavonoids from the roots of Edgew with anti-inflammatory activity.
Nat Prod Res
December 2024
Chongqing Key Laboratory of New Drug Screening from Traditional Chinese Medicine, Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City & Southwest University, SWU-TAAHC Medicinal Plant Joint R&D Centre, College of Pharmaceutical Sciences, Southwest University, C
Himalaflavones F () and G (), two new flavonoids, along with eight known ones ()were isolated from the roots of Edgew. The chemical structures of these compounds were elucidated by 1D/2D NMR, UV and HR-ESI-ME data. Meanwhile, the anti-inflammatory activities of all isolates were test by using Griess method.
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