An Augmented Reality Visor for Intraoperative Visualization, Guidance, and Temperature Monitoring Using Fluorescence.

J Biophotonics

Nanoparticle Systems Engineering Laboratory, Department of Mechanical and Process Engineering (D-MAVT), Institute of Energy and Process Engineering (IEPE), ETH Zurich, Zurich, Switzerland.

Published: February 2025


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Article Abstract

Fluorescence-guided surgeries, including tumor resection and tissue soldering, are advancing the frontiers of surgical precision by offering enhanced control that minimizes tissue damage, improving recovery and outcomes. However, integrating fluorescence visualization with real-time temperature monitoring remains a challenge, limiting broader clinical use. We address this issue with an augmented reality (AR) visor that combines nanomaterial excitation, fluorescence detection, and temperature monitoring. Using advanced fluorescent nanoparticles like indocyanine green-doped particles and carbon nanotubes, the visor provides a comprehensive view of both the surgical field and sub-surface conditions invisible to the naked eye. This integration improves the safety and efficacy of fluorescence-guided surgeries, including laser tissue soldering, by ensuring optimal temperatures and laser guidance in real time. The presented technology enhances existing surgical techniques and supports the development of new strategies and sensing technologies in areas where traditional methods fall short, marking significant progress in precision surgery and potentially improving patient care.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11793943PMC
http://dx.doi.org/10.1002/jbio.202400417DOI Listing

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