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Aims: To objectively characterize the spatial-velocity dynamics of the QRS-loop in the vectorcardiogram (VCG) of patients with acute myocardial infarction (AMI).
Methods: VCG was constructed as a space curve directly with three quasi-orthogonal leads I, aVF and V2 recorded by conventional ECG of 25 healthy individuals and 50 AMI patients. Spatial velocity (SV) of the dynamic QRS loop, spatial distance (SD), and spatial magnitude (SM) were recorded, along with axis-specific component attributes of vector magnitude such as ΔX, ΔY, and ΔZ.
Results: Decreased SV (12-25%, = 0.02) and SD (10-26%, = 0.02) and altered spatial propagation patterns of ventricular vectors in AMI were recorded, with changes in specific axes based on infarct location. Significant vector changes were found in the Y-Axis in IWMI ( = 0.005) and X-Axis in cases of AWMI ( = 0.02), as compared to controls. There was no apparent alteration of SM in AMI.
Conclusion: Decreased SV and SD without any significant alteration of SM indicates close approximation and clustering of the tips of the ventricular vector in AMI. This may be due to dilation, thinning, and stress of the ventricular wall in early post infarction ventricular remodeling, along with relative ischemia due to associated tachycardia and higher myocardial oxygen demand.
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http://dx.doi.org/10.1080/14796678.2024.2440257 | DOI Listing |
Clin Res Cardiol
September 2025
Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Essen, Germany.
Objectives: We investigated changes in lipid-lowering drug prescriptions in Germany as a whole and in the 16 federal states over the last 13 years and their association with hospitalization rates for acute myocardial infarction.
Design: Ecological study.
Setting: Nationwide German hospitalization, Diagnosis-Related Groups Statistic.
Cureus
August 2025
Department of Emergency Medicine, Centre Hospitalier Universitaire de Charleroi, Lodelinsart, BEL.
A 37-year-old man, previously healthy, presented to the emergency department with retrosternal chest pain for 24 hours, in the context of watery diarrhea (five to six times a day), abdominal pain, and fever evolving over four days. Following medical assessment, a diagnosis of myopericarditis due to infection was made. This complication of infection is rare and poorly described, but given its rising incidence, increased vigilance is necessary.
View Article and Find Full Text PDFEur Heart J Case Rep
September 2025
Department of Radiology, The First Affiliated Hospital of Bengbu Medical University, No. 287 Changhuai Road, Bengbu, Anhui Province 233004, China.
Background: Fulminant myocarditis (FM) is a rare but serious inflammatory disease of the heart that should be considered for extracorporeal membrane oxygenation (ECMO) supportive therapy when it occurs. The diagnosis of FM is made more difficult in the context of Marfan's syndrome combined with aortic root dilation. We report a case of a patient on ECMO support and with comorbid Marfan's syndrome who was finally diagnosed with FM after computed tomography angiography (CTA) differentiated between FM, coronary artery disease, and aortic root dilation.
View Article and Find Full Text PDFFront Cardiovasc Med
August 2025
Pernambuco Cardiac Emergency Hospital, University of Pernambuco (PROCAPE, UPE), Recife, Brazil.
Atherosclerosis is the most important etiology of acute myocardial infarction, which is considered an inflammatory disease with specific cellular and molecular responses. Recent research has linked hematological variables as biomarkers of the severity of coronary artery disease. Studies suggest that nucleated red blood cells (NRBCs), neutrophil to lymphocyte ratio (NLR), and mean platelet volume (MPV) may serve as components of a laboratory model or hematological scoring system for in-hospital surveillance.
View Article and Find Full Text PDFFront Cardiovasc Med
August 2025
Department of Cardiology, Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University, Shanghai, China.
Background: Acute myocardial infarction in the elderly often leads to significant left ventricular structural remodeling, which adversely affects prognosis. This study aims to evaluate the effects of intensive rosuvastatin therapy on markers of ventricular remodeling and cardiac function following percutaneous coronary intervention (PCI) in elderly patients with ST-segment elevation myocardial infarction (STEMI).
Methods: This study enrolled 100 patients aged ≥60 years with STEMI who underwent emergency PCI.