Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: The aim of the study was to examine the association between alcohol consumption and stroke in Nigeria and Ghana.
Methods: The study is a multicentre, case-control study. Cases included consenting adults 18 years of age and older with acute stroke and controls were age-and -gender -matched stroke -free adults. Alcohol consumption was self-reported. The participants were classified into three alcohol-drinking status, which included abstainers, former drinkers, and current drinkers. The current drinkers were further classified into different alcohol drinking levels, including infrequent, light, moderate, heavy, and binge drinkers. Conditional logistic regression was used to determine associations between the drinking status and stroke, and the association between the different levels of current alcohol consumption and stroke. Five models were evaluated. Model 1 was unadjusted. Model 2 was adjusted for demographic characteristics. Model 3 included Model 2, lifestyle and psychosocial characteristics. Model 4 included Model 3 and dietary characteristics. Model 5 included Model 4 and metabolic characteristics.
Results: A total of 7368 participants took part in the study. Half were stroke participants, and half were control participants. On the associations between drinking status and stroke, respectively, former drinkers showed no significant association with stroke. However, a significant association was observed between current drinkers and stroke in Models 1 and 2, with an odds ratio of 1.19 (95% CI: 1.04-1.38; p < 0.05) and 1.17 (95% CI: 1.01-1.36; p < 0.05), respectively. Regarding the various levels of current alcohol drinking and their association with stroke, no significant association was observed between light drinking and stroke in Model 5. In contrast, moderate drinkers, binge drinkers, and heavy drinkers showed a persistent and significant association with stroke respectively.
Conclusion: There is a significant association between stroke and current alcohol consumption, especially among heavy, binge, and moderate drinkers.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12092175 | PMC |
| http://dx.doi.org/10.1177/17474930241308458 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Hippocampal Cofilin and CFL1 gene variants are linked to Alcohol Use Disorder phenotypes.
Mol Psychiatry
September 2025
Nencki Institute of Experimental Biology of Polish Academy of Sciences, 3 Pasteur St., Warsaw, 02-093, Poland.
Alcohol use disorder (AUD) is characterized by pathological motivation to consume alcohol and cognitive inflexibility, leading to excessive alcohol seeking and use. In this study, we investigated the molecular correlates of impaired extinction of alcohol seeking during forced abstinence using a mouse model of AUD in the automated IntelliCage social system. This model distinguished AUD-prone and AUD-resistant animals based on the presence of ≥2 or <2 criteria of AUD, respectively.
View Article and Find Full Text PDFGenetically modeled GLP1R and GIPR agonism reduce binge drinking and alcohol-associated phenotypes: a multi-ancestry drug-target Mendelian randomization study.
Mol Psychiatry
September 2025
Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Pharmacological modulation of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) through dual GIP/GLP-1 receptor agonists, commonly used for diabetes and obesity, shows promise in reducing alcohol consumption. We applied drug-target Mendelian randomization (MR) using genetic variation at these loci to assess their long-term effects on problematic alcohol use (PAU), binge drinking, alcohol misuse classifications, liver health, and other substance use behaviors. Genetic proxies for lowered BMI, modeling the appetite-suppressing and weight-reducing effects of variants in both the GIPR and GLP1R loci ("GIPR/GLP1R"), were linked with reduced binge drinking in the primary (β = -0.
View Article and Find Full Text PDFExploring the role of gender on treatment outcomes in older adults with alcohol use disorder.
Alcohol Clin Exp Res (Hoboken)
September 2025
Research Unit of Psychiatry, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
Background: Alcohol use disorder (AUD) among older adults, particularly with respect to gender differences in treatment outcomes, remains underexplored. Our objective was to explore gender differences in AUD treatment outcomes among older adults, focusing on continuous measures (e.g.
View Article and Find Full Text PDFInfluence of alcohol consumption on resilience, emotional intelligence, and self-esteem in army personnel: A cross-sectional study.
Mil Psychol
September 2025
Department of Educational Sciences, University of La Rioja, Logroño, Spain.
Military personnel face physical and psychological challenges that may contribute to unhealthy behaviors, such as alcohol consumption. This study aimed to analyze the psychological variables of emotional intelligence, resilience, and self-esteem among Spanish Army personnel, as well as their relationship with the daily consumption or non-consumption of at least one alcoholic beverage. A cross-sectional descriptive study was conducted with a sample of 739 military personnel, with a mean age of 33.
View Article and Find Full Text PDFWearable device-measured circadian rest-activity rhythm with mortality risk in patients with cancer.
BMJ Health Care Inform
September 2025
Center for Sleep and Circadian Medicine, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China
Objectives: The objectives were to examine the associations between accelerometer-measured circadian rest-activity rhythm (CRAR), the most prominent circadian rhythm in humans and the risk of mortality from all-cause, cancer and cardiovascular disease (CVD) in patients with cancer.
Methods: 7456 cancer participants from the UK Biobank were included. All participants wore accelerometers from 2013 to 2015 and were followed up until 24 January 2024, with a median follow-up of 9.