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Purpose: The impact of non-fixation of mesh in transabdominal preperitoneal (TAPP) inguinal hernia repair has not been fully assessed. The aim of this meta-analysis was to comprehensively compare the clinical outcomes of non-fixation and fixation of mesh in TAPP to determine whether non-fixation could affect the outcomes.
Methods: PubMed, Embase and CENTRAL were searched for studies on TAPP repair of inguinal hernia and mesh fixation published up to June 2023. The literature search was completed on June 22, 2023. Randomized controlled trials that compared perioperative outcomes between mesh fixation and non-fixation without using self-gripping mesh were included. The primary outcome measures were recurrence and evaluation of postoperative pain, while secondary outcome measures included time to normal activity, infection rate and formation of seroma. Subgroup analyses and sensitivity analysis were also conducted.
Results: Six randomized controlled trials were included, involving 679 patients who underwent TAPP with non-fixation and 964 patients with fixation of mesh. There was no significant difference in recurrence between the two groups (RR: 0.83; 95% CI, 0.29-2.39, P = 0.73). The non-fixation group had less pain than the fixation group at 6 months postoperatively (MD: -0.16; 95% CI, -0.23--0.10, P < 0.0001). Additionally, there was no significant difference in the time to return to normal activity or rates of infection or seroma formation between the two groups (MD: -4.95; 95% CI, -11.36-1.45, P = 0.13; RR: 1.18; 95% CI, 0.39-3.62, P = 0.77; RR: 0.94; 95% CI, 0.63-1.40, P = 0.75).
Conclusion: Based on the current evidence, non-fixation without using self-gripping mesh may not affect the efficacy of TAPP. It does not increase recurrence rate and may result in less postoperative pain in inguinal hernia with small hernia defect (less than 3cm).
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11623461 | PMC |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0314334 | PLOS |
Pol Merkur Lekarski
September 2025
DEPARTMENT OF GENERAL, ONCOLOGIC AND METABOLIC SURGERY, INSTITUTE OF HEMATOLOGY AND TRANSFUSION MEDICINE, WARSAW, POLAND.
Objective: Aim: The study aims to evaluate the impact of the ONSTEP technique on the intensity of the systemic inflammatory response syndrome (SIRS) and the outcomes of inguinal hernia treatment compared to the Lichtenstein technique. .
Patients And Methods: Materials and Methods: In 41 men randomized into 2 study groups, unilateral inguinal hernia repair was performed using the ONSTEP technique in group O and the Lichtenstein technique in group L.
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Small intestinal diverticulosis is a rare condition, often asymptomatic until complicated with diverticulitis, bleeding, obstruction, or perforation. It predominantly affects elderly men and may present concomitantly with colon diverticulosis. We report the case of a 94-year-old Hispanic woman brought to the emergency department presenting with an acute abdomen.
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View Article and Find Full Text PDFAnaesthesia
September 2025
Department of Applied Health Sciences, School of Health Sciences, University of Birmingham, UK.
Introduction: Restoration of surgical capacity is essential to post-COVID-19 recovery. This study explored the use and safety of anaesthesia options for inguinal hernia surgery, a common tracer condition, to describe current global practice and highlight opportunities to build the capacity of health systems.
Methods: This is a secondary analysis of an international prospective cohort study of consecutive patients who underwent elective inguinal hernia surgery.
Surg Case Rep
September 2025
Department of Surgery, Kyushu University Beppu Hospital, Beppu, Oita, Japan.
Introduction: Glycogen storage disease type IX (GSD type IX) is caused by a deficiency in phosphorylase b kinase (PHK) and is classified into hepatic (IXa-c) and muscular (IXd) subtypes. GSD type IXd leads to exercise intolerance, rhabdomyolysis, and myoglobinuria owing to impaired glycogen breakdown. It is a rare and mild metabolic disorder, with only 19 reported cases of mutations.
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