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Objective: This study examined changes in nutritional status, fatigue, and quality of life, and identified longitudinal factors influencing changes in quality of life in patients with pancreatic cancer before and 12 months after surgery.
Methods: A longitudinal, correlational, single-group study was conducted on 89 patients with operable pancreatic cancer in Taiwan. Data were collected preoperatively (T0) and at 3 (T1), 6 (T2), and 12 (T3) months post-surgery using questionnaires- Mini Nutritional Assessment, Fatigue Symptom Inventory, and Functional Assessment of Cancer Therapy-General-and through bioelectrical impedance analysis, handgrip strength measurement, and the 30-s sit-to-stand test. Generalized estimating equation models were used to analyze variable changes and associated factors.
Results: Body weight (T1, p < 0.01; T2, p < 0.01; T3, p < 0.01), visceral fat mass (T1, p < 0.01; T2, p < 0.01; T3, p < 0.01), and handgrip strength (T1, p < 0.01; T2, p < 0.01; T3, p < 0.01) decreased significantly after surgery. The quality of life significantly improved at T2 and T3 (T2, p = 0.04; T3, p = 0.04). Lower visceral fat mass (β = -2.27, p < 0.01), better overall nutritional status (β = 1.54, p < 0.01), and lower fatigue (β = -0.26, p < 0.01) were associated with higher quality of life from T0-T3.
Conclusions: Patients with pancreatic cancer should have their nutritional status and fatigue assessed early and continuously for at least 12 months post-surgery. Early preoperative interventions that can reduce visceral fat mass, combat malnutrition, and alleviate fatigue are recommended.
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http://dx.doi.org/10.1016/j.apnr.2024.151858 | DOI Listing |
JMIR Rehabil Assist Technol
September 2025
Department of Computer Science, Faculty of Technology, Art and Design, OsloMet - Oslo Metropolitan University, Oslo, Norway.
Background: Over the past decade, the proportion of the world's population aged ≥65 years has grown exponentially, presenting significant challenges, such as social isolation and loneliness among this population. Assistive technologies have shown potential in enhancing the quality of life for older adults by improving their physical, cognitive, and communication abilities. Research has shown that smart televisions are user-friendly and commonly used among older adults.
View Article and Find Full Text PDFJMIR Res Protoc
September 2025
Institute for Collaboration on Health, Intervention, and Policy, University of Connecticut, Storrs, CT, United States.
Background: Children in the United States have poor diet quality, increasing their risk for chronic disease burden later in life. Caregivers' feeding behaviors are a critical factor in shaping lifelong dietary habits. The Strong Families Start at Home/Familias Fuertes Comienzan en Casa (SFSH) was a 6-month, home-based, pilot randomized-controlled feasibility trial that aimed to improve the diet quality of 2-5-year-old children and promote positive parental feeding practices among a predominantly Hispanic/Latine sample.
View Article and Find Full Text PDFNeuro Endocrinol Lett
September 2025
Department of Pediatric Neurology, Cukurova University Faculty of Medicine, Adana, Turkey.
Objective: It is important to raise awareness of the nutritional problems that can be overlooked during the follow-up visits with children who suffer from neuromuscular diseases, as these dietary differences may lead to additional neurological and systemic problems and impair the quality of life of the patient. The aim of this study was to evaluate the nutritional status of children with neuromuscular disorders and to prevent possible complications by recognizing possible nutritional problems in advance.
Methods: Patients who applied to the outpatient clinic at Cukurova University, Faculty of Medicine, Department of Pediatric Neurology beginning in April 2022 with a neuromuscular disorder diagnosis were followed up with and were included in the study.
Cardiol Rev
September 2025
Departments of Cardiology and Medicine, Westchester Medical Center and New York Medical College, Valhalla, NY.
Heart failure (HF) remains one of the leading causes of 30-day hospital readmissions, presenting a major challenge to healthcare systems worldwide. This comprehensive review synthesizes recent evidence on effective strategies to reduce readmission rates through patient education, self-care interventions, and systemic reforms. Structured education-particularly when reinforced postdischarge through methods like teach-back, tele-coaching, and home visits-has consistently demonstrated improved self-management, symptom recognition, and quality of life.
View Article and Find Full Text PDFEur J Gastroenterol Hepatol
September 2025
Department of General Medicine, Affiliated Anqing First People's Hospital of Anhui Medical University, Anqing, Anhui, China.
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-associated death globally. Second-line therapies are crucial for improving survival and quality of life among individuals suffering from advanced HCC who have not responded to first-line therapies. This study sought to evaluate the safety and efficacy of different second-line therapies for advanced HCC by network meta-analysis.
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