Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

In this paper, we present the demonstration of a cavity-dumped Kerr-lens mode-locked femtosecond oscillator based on an Yb:CALYO crystal for the first time. With the assistance of an SESAM, the Kerr-lens mode-locked Yb:CALYO laser delivered pulses with an average power of 2.8 W at a repetition rate of 61.3 MHz, corresponding to a pulse energy of 45.6 nJ. By employing a Pockels Cell consisting of dual β-BBO crystals and a thin film polarizer for cavity dumping, laser pulses of 280 nJ were achieved at both 1 MHz and 10 kHz repetition rates. The shortest pulse duration measured was 233 fs without external compression, resulting in a peak power of 1.06 MW.

Download full-text PDF

Source
http://dx.doi.org/10.1364/OE.537391DOI Listing

Publication Analysis

Top Keywords

ybcalyo laser
8
kerr-lens mode-locked
8
cavity-dumped femtosecond
4
femtosecond ybcalyo
4
laser based
4
based sesam
4
sesam assisted
4
assisted kerr-lens
4
kerr-lens mode
4
mode locking
4

Similar Publications

Microbial contamination of absorbable collagen membranes used in guided bone regeneration (GBR) may compromise healing outcomes. This study aimed to investigate whether the minimum inhibitory concentration (MIC) of hydrogen peroxide (HO) can improve the antibacterial effect of indocyanine green (ICG)-mediated antimicrobial photodynamic therapy (PDT) on absorbable collagen membranes while reducing the need for high HO concentrations. A laboratory-based model was developed using Streptococcus sanguinis and Staphylococcus aureus.

View Article and Find Full Text PDF

IL12-based phototherapeutic nanoparticles through remodeling tumor-associated macrophages combined with immunogenic tumor cell death for synergistic cancer immunotherapy.

Biomater Sci

September 2025

Key Laboratory of Biomaterials and Nanotechnology for Cancer Immunotherapy, The Tianjin Key Laboratory of Biomaterials, Institute of Biomedical Engineering, Peking Union Medical College & Chinese Academy of Medical Sciences, Tianjin, 300192, China.

Various cancer therapeutic strategies have been designed for targeting tumor-associated macrophages (TAMs), but TAM reprogramming-based monotherapy is often clinically hindered, likely due to the lack of a coordinated platform to initiate T cell-mediated immunity. Herein, we fabricated reactive oxygen species (ROS)-responsive human serum albumin (HSA)-based nanoparticles (PEG/IL12-IA NPs) consisting of indocyanine green (ICG), arginine (Arg), and interleukin 12 (IL12). Upon laser irradiation, the nanoparticles were found to be able to dissociate, thus facilitating the release of IL12.

View Article and Find Full Text PDF

Purpose: To compare the efficacy of intraoral (IOPBM) and extraoral photobiomodulation (EOPBM) protocols for the prevention and treatment of oral mucositis (OM) in patients with oral or oropharyngeal squamous cell carcinoma (SCC) to submitted radiotherapy (RT).

Methods: This randomized, blinded, multicenter clinical trial enrolled 58 patients with oral or oropharyngeal SCC, who were allocated into two groups matched by treatment type, clinical stage, and RT modality. Group I (IOPBM) received intraoral photobiomodulation (PBM) with a continuous InGaAlP diode laser (660 nm, 100 mW, 0.

View Article and Find Full Text PDF

Introduction: Women who experience postpartum hemorrhage (PPH) after giving birth rapidly lose blood, which may lead to shock or death without immediate intervention. PPH most often results from uterine atony, when the uterus fails to contract after delivery. Worldwide, PPH causes 10 deaths hourly, with most deaths occurring in low-income settings.

View Article and Find Full Text PDF

Time-resolved data acquisition is crucial for compositional analysis using Laser-Induced Breakdown Spectroscopy (LIBS). It can be managed by adjusting the delay time and gate width of the spectrometer. This study describes the compositional analysis of molybdenum (Mo) ore utilizing charge coupled device (CCD) and intensified charge-coupled device (ICCD) based LIBS systems.

View Article and Find Full Text PDF