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The primary purpose of this review is to explore the green synthesis of silver nanoparticle (AgNP) using natural biomolecules derived from marine sources. This review aims to evaluate the effectiveness of environmentally friendly approaches for synthesizing AgNPs and to examine their potential applications across various fields such as medicine, biotechnology, and environmental remediation. The key research question focuses on understanding how marine biomolecules, including polysaccharides, proteins, enzymes, amino acids, alkaloids, and vitamins, contribute to the formation of AgNPs and how these green-synthesized nanoparticles retain their functional properties. This review systematically examines current literature on the green synthesis of AgNPs, focusing on marine-derived biomolecules such as polysaccharides, proteins, and alkaloids. The methodology includes analyzing green synthesis techniques and comparing them with traditional chemical methods to highlight environmental benefits and overall efficiency. Various marine species, such as seagrass and seaweed, are explored as potent agents in the reduction of silver ions. The findings reveal that green synthesis of AgNPs using marine biomolecules is not only environmentally sustainable but also retains the desirable properties of the nanoparticles, such as antimicrobial, antioxidant, and anticancer activities. Additionally, the green-synthesized AgNPs show significant potential applications in mosquito control, wound healing, and anticancer therapies. Green synthesis of AgNPs using marine sources presents a viable and sustainable alternative to conventional chemical methods, significantly reducing the environmental impact of nanoparticle production while ensuring biocompatibility and functional integrity. This approach holds promise for diverse applications in biomedicine, environmental remediation, and beyond. Further research is recommended to address challenges in scaling up production and commercialization.
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http://dx.doi.org/10.1007/s00210-024-03547-0 | DOI Listing |
Environ Monit Assess
September 2025
Department of Civil Engineering, Faculty of Engineering, Karpagam Academy of Higher Education, Pollachi Main Road, Eachanari Post, Coimbatore, Tamil Nadu, 641021, India.
Synthetic dyes, such as Congo red (CR), pose serious threats to human health and aquatic ecosystems because of their carcinogenicity and resistance to degradation, necessitating the development of efficient and eco-friendly remediation strategies. In this study, silver nanoparticles (AgNPs) were synthesized via a green method using Ocimum sanctum (holy basil) leaf extract and applied for CR dye removal from aqueous solutions. The adsorption process was optimized using response surface methodology (RSM) based on Box-Behnken design (BBD), evaluating the influence of key parameters including pH, AgNP dosage, initial dye concentration, contact time, and temperature.
View Article and Find Full Text PDFNPJ Biofilms Microbiomes
September 2025
Imperial College Parturition Research Group, Institute of Reproductive and Developmental Biology, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
The mechanisms by which vaginal microbiota shape spontaneous preterm birth (sPTB) risk remain poorly defined. Using electronic clinical records data from 74,913 maternities in conjunction with metaxanomic (n = 596) and immune profiling (n = 314) data, we show that the B blood group phenotype associates with increased risk of sPTB and adverse vaginal microbiota composition. The O blood group associates with sPTB in women who have a combination of a previous history of sPTB, an adverse vaginal microbial composition and pro-inflammatory cervicovaginal milieu.
View Article and Find Full Text PDFNucleic Acids Res
September 2025
Biomolecular Sciences Institute, Florida International University, Miami, FL 33199, United States.
Supercoiled (Sc) circular DNA, such as plasmids, are essential in molecular biology and hold strong therapeutic potential. However, they are typically produced in Escherichia coli, resulting in bacterial methylations, unnecessary sequences, and contaminants that hinder certain applications including clinical uses. These limitations could be avoided by synthesizing plasmids entirely in vitro, but synthesizing high-purity Sc circular DNA biochemically remains a significant technical challenge.
View Article and Find Full Text PDFInt J Sport Nutr Exerc Metab
September 2025
Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, VIC, Australia.
Technological innovations can provide cyclists and their support team additional data. These data have potential to improve understanding of performance determinants and could be used to identify and tailor nutritional strategies to improve cycling performance. This potential, however, is dependent on the quality, interpretation, and practical use of the data generated.
View Article and Find Full Text PDFJ Lipid Res
September 2025
Department of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, Ontario, Canada, M5S 1A8. Electronic address:
Young females have higher circulating docosahexaenoic acid (DHA) levels than males, though the metabolic basis remains incompletely understood. Building on previous findings demonstrating higher hepatic synthesis of the DHA precursor, docosapentaenoic acid (DPAn-3) in males, this study extends the investigation to n-3 PUFA turnover in extrahepatic tissues of male and female C57BL/6N mice using compound-specific isotope analysis (CSIA). Animals were fed a 12-week diet enriched in either α-linolenic acid (ALA), eicosapentaenoic acid (EPA), or DHA, starting with a 4-week phase containing low carbon-13 (δC)-n-3 PUFA, followed by an 8-week phase with high δC-n-3 PUFA (n = 4 per diet, time point, sex).
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