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Shaping of ceramics is crucial. Current techniques cannot easily and rapidly shape ceramics without weakening their properties, especially for piezoceramics. We present an ultrafast ceramic shaping method that leverages thermomechanical fields to deform and sinter ceramic powder compacts into complex-shaped ceramics. The shape-forming process hinges on: (1) the implementation of a precise thermal field to activate optimal deformability, and (2) the application of sufficient mechanical loads to guide deformation. We employ a programmable carbon-felt Joule heater that concurrently function as mechanical carriers, effectively transferring applied loads to the ceramic powder compacts. Using this ultrafast shaping and sintering (USS) method, we fabricate barium titanate (BT) piezoceramics in twisted shape, arch shape and with micropatterns. The USS method is energy-friendly (requiring approximately 1.06 kJ mm) and time-efficient (in several minutes level). Overall, the USS method offers an effective solution for shaping ceramics and extends them to 3D geometries with enhanced versatility.
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http://dx.doi.org/10.1038/s41467-024-54393-w | DOI Listing |
AJNR Am J Neuroradiol
September 2025
Department of Fetal Maternal Medicine (S.E., T.E.), Leeds General Infirmary, Leeds, South Yorkshire, United Kingdom of Great Britain and Northern Ireland.
Background And Purpose: Many studies have shown that in utero MR imaging (iuMRI) is a valuable adjunct to ultrasonography studies (USS) when a brain abnormality has been shown on USS. There is an increasing tendency, however, for fetal maternal experts to use iuMRI in fetuses with small heads but no evident brain abnormality on USS. The diagnostic and clinical value for that approach is not known at present, and the aim of this study is to close that gap in medical knowledge.
View Article and Find Full Text PDFPlacenta
August 2025
Facultad de Ciencias, Universidad San Sebastián, Santiago, 7510157, Chile. Electronic address:
Unlabelled: Maternal physiological hypercholesterolemia (MPH; total cholesterol (TC)≤280 mg/dL) occurs during pregnancy to support fetal growth. When TC exceeds this threshold, this condition is recognized as maternal supraphysiological hypercholesterolemia (MSPH), which is associated with endothelial dysfunction in the maternal and fetoplacental vasculature. Placenta-derived extracellular vesicles (EVs), which mediate intercellular communication during pregnancy, may contribute to MSPH by affecting endothelial cells.
View Article and Find Full Text PDFSci Rep
August 2025
Laboratorio de Neuroinmunología, Facultad de Ciencias, Universidad San Sebastián, sede Concepción, Concepción, Chile.
The search for pathological biomarkers in biological fluids that can provide valuable insight into an individual's health status, is a relevant area of research for multiple pathologies. Currently, the use of proteomics for the identification of differences in protein expression profiles between samples from healthy subjects and patients, has emerged as a powerful strategy to improve the current diagnosis of various pathologies or propose novel therapeutic approaches. Among the biological fluids from which new pathological biomarkers can be identified, tear secretion is highly attractive, since it can be collected non-invasively and could better concentrate proteins that sensitively reflect allergic responses, owing to their exposure to environmental factors and its connection to the respiratory system.
View Article and Find Full Text PDFAutism Res
August 2025
Escuela de Obstetricia, Facultad de Ciencias para el Cuidado de la Salud, Universidad San Sebastián (USS), Santiago, Chile.
Some reports show that children exposed to hyperandrogenemia or hyperglycemic states in utero are more prone to be diagnosed with autism spectrum disorder (ASD). This systematic review and meta-analysis aim to assess the association between Polycystic Ovary Syndrome (PCOS) or gestational diabetes (GD) and ASD. A systematic review (1980-2023) in Web of Science, PubMed and Scopus, using specific search terms "gestational diabetes", "polycystic ovary syndrome," "neurodevelopmental disorder" and "autism spectrum disorder" was performed.
View Article and Find Full Text PDFJ Vasc Surg
August 2025
Division of Vascular Surgery and Endovascular Therapy, Department of Surgery, Yale School of Medicine, New Haven, CT. Electronic address:
Objective: Frailty can be used to estimate perioperative and long-term mortality risk in octogenarians undergoing elective endovascular abdominal aortic aneurysm repair (EVAR). Its association with functional decline, an important surrogate of quality of life in older adults, has not been well studied in this population. We aimed to evaluate whether preoperative factors such as frailty are associated with one-year functional decline after elective EVAR in octogenarians and to compare the performance of three different frailty assessments.
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