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Investigating trends in water use efficiency (WUE) and its causality is critical for understanding ecosystem behaviors. Although WUE has shown nonlinear changes in the last several decades across most global ecosystems, the majority of available studies have focused on its linear trend. This study attempted to accurately attribute the linear and nonlinear variations in WUE using normalized driving factors in the Partial Derivative (PD) equation to develop a Normalized Partial Derivative model (NPD-model). Two linear trends obtained from the Linear Regression (LR) and Non-Parametric (NP) and a nonlinear trend obtained from the Ensemble Empirical Mode Decomposition (EEMD) are employed in the NPD-model for attributing WUE change in China. The individual and relative responses of driving factors to WUE change during 2000-2018 are quantified using the China version of the PML-V2 evapotranspiration and gross primary productivity products. The results show that the nonlinear EEMD-based NPD-model with an R of 0.83, performs best compared to the LR- and NP-based NPD-models, which have R values of 0.64 and 0.7, respectively. WUE increased monotonically in most areas of all vegetation types, with high variability observed in grassland and shrubland. The EEMD-based attribution analysis indicates that leaf area index is the leading factor in regulating WUE in China, followed by CO and climate. The relative contributions revealed that increased WUE in most of China is dominated by the combination of vegetation and environmental factors, covering more than 80% of the study area. These contribution results, however, are largely different from those obtained using the LR- and NP-based NPD-models, as 52% of the study area exhibits cyclic variation in WUE. Therefore, the nonlinear EEMD-based NPD-model provides excellent spatiotemporal attribution of WUE through its driving factors, which is crucial for understanding the ecosystem response to changing environments, potentially assisting in ecosystem and water resource management.
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http://dx.doi.org/10.1016/j.jenvman.2024.123323 | DOI Listing |
Transl Psychiatry
September 2025
Department of Human Sciences, The Ohio State University, Columbus, OH, USA.
A ketogenic diet (KD) has shown promise as an adjunctive therapy for neurological and neuropsychiatric disorders, including bipolar disorder and major depressive disorder (MDD). We examined tolerance for a KD in young adults with MDD and assessed symptoms of depression and metabolic health. Students (n = 24) with a confirmed diagnosis of MDD at baseline receiving standard of care counseling and/or medication treatment were enrolled in a 10-12 week KD intervention that included partial provision of ketogenic-appropriate food items, frequent dietary counseling, and daily morning tracking of capillary R-beta-hydroxybutyrate (R-BHB).
View Article and Find Full Text PDFTalanta
September 2025
State Key Laboratory of Chemistry for NBC Hazards Protection, 102205, Beijing, China. Electronic address:
Organophosphorus nerve agents (OPNAs), including G-agents, EGA (ethyltabun, phosphonamidic acid, P-cyano-N,N-diethyl-, ethyl ester) and V-agents, VM (O-ethyl S-(2-diethylaminoethyl) phosphonothiolate), are highly toxic chemical warfare agents (CWAs) with severe risks to human health and environmental security. This study proposes a chemometric-driven framework for forensic tracing of their synthetic pathways using high-resolution GC × GC-TOFMS. By integrating advanced statistical analysis, we identified 160 synthesis-associated chemical attribution signatures (CAS) for EGA and 138 process-specific CAS for VM, with 11 overlapping markers, including ethoxyphosphates and diethylaminoethylamine derivatives.
View Article and Find Full Text PDFCancer Genet
August 2025
Clinical Hematology and BMT Unit, Bahrain Oncology Center, Road 2835, Block 228, P.O. Box 24343, Busaiteen, Kingdom of Bahrain. Electronic address:
Complex chromosomal changes in Acute Myeloid Leukemia (AML) are highly heterogeneous, with disease progression shaped by both the number and nature of abnormalities. Rarely do, multiple unrelated clones with independent chromosomal changes coexist at diagnosis. Present study showcases a comprehensive characterization of two cytogenetically distinct complex clones in AML, driven by non-cyclic and chromoplexy mechanisms, highlighting their co-existence with key molecular alterations (TP53, NF1, DNMT3A, TET2) along with their potential contribution to clonal evolution.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
September 2025
Vellore Institute of Technology, Vellore, 632014, Tamil Nadu, India.
The significant global energy consumption strongly emphasizes the crucial role of net-zero or green structures in ensuring a sustainable future. Considering this aspect, incorporating thermal insulation materials into building components is a well-accepted method that helps to enhance thermal comfort in buildings. Furthermore, integrating architectural components made from solid refuse materials retrieved from the environment can have significant environmental benefits.
View Article and Find Full Text PDFJ Child Psychol Psychiatry
September 2025
Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Background: Prospective studies of autism family history infants primarily report recurrence and predictors of autism at 3 years. Less is known about ADHD family history infants and later childhood outcomes. We characterise profiles of mid-childhood developmental and behavioural outcomes in infants with a family history of autism and/or ADHD to identify potential support needs and patterns of co-occurrence across domains.
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