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The aim of the present study was to train a natural language processing model to recognize key text elements from research abstracts related to hand surgery, enhancing the efficiency of systematic review screening. A sample of 1600 abstracts from a systematic review of distal radial fracture treatment outcomes was annotated to train the natural language processing model. To assess time-saving potential, 200 abstracts were processed by the trained models in two experiments, where reviewers accessed natural language processing predictions to include or exclude articles. The natural language processing model achieved an overall accuracy of 0.91 in recognizing key text elements, excelling in identifying study interventions. Use of the natural language processing reduced mean screening time by 31% without compromising accuracy. Precision varied, improving in the second experiment, indicating context-dependent performance. These findings suggest that natural language processing models can streamline abstract screening in systematic reviews by effectively identifying original research and extracting relevant text elements. IV.
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http://dx.doi.org/10.1177/17531934241295493 | DOI Listing |
Am J Epidemiol
September 2025
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Tree-based scan statistics (TBSS) are data mining methods that screen thousands of hierarchically related health outcomes to detect unsuspected adverse drug effects. TBSS traditionally analyze claims data with outcomes defined via diagnosis codes. TBSS have not been previously applied to rich clinical information in Electronic Health Records (EHR).
View Article and Find Full Text PDFJ Dent Educ
September 2025
Department of Oral and Maxillofacial Surgery, Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, P. R. China.
Background: Virtual reality (VR) and artificial intelligence (AI) technologies have advanced significantly over the past few decades, expanding into various fields, including dental education.
Purpose: To comprehensively review the application of VR and AI technologies in dentistry training, focusing on their impact on cognitive load management and skill enhancement. This study systematically summarizes the existing literature by means of a scoping review to explore the effects of the application of these technologies and to explore future directions.
Asian J Psychiatr
September 2025
Department of Psychiatry and Mental Health, Faculty of Medicine, Universidad de Chile, Santiago, Chile; Translational Psychiatry Laboratory (Psiquislab), Faculty of Medicine, Universidad de Chile, Santiago, Chile; Millennium Nucleus to Improve the Mental Health of Adolescents and Youths (IMHAY), San
Background: Schizophrenia spectrum disorders often emerge in adolescence or early adulthood and are a leading cause of global disability. Early identification of clinical high‑risk for psychosis (CHR‑P) can reduce comorbidity and shorten untreated psychosis duration, yet clinician‑administered tools (e.g.
View Article and Find Full Text PDFBrief Bioinform
September 2025
College of Computing and Data Science, Nanyang Technological University, 639798, Singapore.
Protein phosphorylation regulates protein function and cellular signaling pathways, and is strongly associated with diseases, including neurodegenerative disorders and cancer. Phosphorylation plays a critical role in regulating protein activity and cellular signaling by modulating protein-protein interactions (PPIs). It alters binding affinities and interaction networks, thereby influencing biological processes and maintaining cellular homeostasis.
View Article and Find Full Text PDFComput Biol Med
August 2025
The First People Hospital of Foshan, Foshan City CN, China. Electronic address:
Brain Tumor Segmentation (BTS) is crucial for accurate diagnosis and treatment planning, but existing CNN and Transformer-based methods often struggle with feature fusion and limited training data. While recent large-scale vision models like Segment Anything Model (SAM) and CLIP offer potential, SAM is trained on natural images, lacking medical domain knowledge, and its decoder struggles with accurate tumor segmentation. To address these challenges, we propose the Medical SAM-Clip Grafting Network (MSCG), which introduces a novel SC-grafting module.
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