98%
921
2 minutes
20
Deep networks for 3D point clouds have achieved remarkable success in classification task but remain vulnerable to geometric variations resulting from inconsistent data acquisition procedures. This leads to significant performance degradation when models trained on a source domain are tested on out-of-distribution target domains, highlighting the challenges of 3D domain generalization and adaptation. In this paper, we introduce a novel Multi-Scale Part-based feature Representation, dubbed MSPR, as a generalizable representation for point cloud domain generalization and adaptation. Rather than relying on global shape feature, we align the part-level features of shapes at different scales to a set of learnable part-template features that encode local geometric structures shared between the source and the target domains. Specifically, shapes from different domains are organized into part-level features at various scales and then aligned to the part-template features. To balance the generalization and discrimination abilities of parts at different scales, we further design a cross-scale feature fusion module to exchange information between aligned part-based features at different scales. The fused part-based representations are finally aggregated by a part-based feature aggregation module. To improve the robustness of the aligned part-based representations and global shape representation to geometry variations, we further propose a Contrastive Learning framework on Shape Representation (CLSR). Experiments are conducted on 3D domain generalization and adaptation benchmarks for point cloud classification. Extensive experiments on 3D domain generalization and adaptation benchmarks demonstrate that proposed approach outperforms previous state-of-the-art methods in both tasks. Ablation studies confirm the effectiveness of the components in our model.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1109/TPAMI.2024.3496670 | DOI Listing |
BMC Psychiatry
September 2025
Department of Cognitive Neuroscience, Faculty of Biology, Bielefeld University, Bielefeld, Germany.
Obsessive-compulsive disorder (OCD) is a chronic and disabling condition affecting approximately 3.5% of the global population, with diagnosis on average delayed by 7.1 years or often confounded with other psychiatric disorders.
View Article and Find Full Text PDFSci China Life Sci
September 2025
MOE Key Laboratory of Bioinformatics and Center for Plant Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Tomato brown rugose fruit virus (ToBRFV) overcomes all known tomato resistance genes, including the durable Tm-2, posing a serious threat to global tomato production. Here, we employed in vitro random mutagenesis to evolve the Tm-2 leucine-rich repeat (LRR) domain and screened ∼8,000 variants for gain-of-function mutants capable of recognizing the ToBRFV movement protein (MP) and triggering hypersensitive cell death. We identified five such mutants.
View Article and Find Full Text PDFCell Death Differ
September 2025
Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.
Multiple sclerosis (MS) is a chronic autoimmune disorder of the central nervous system (CNS) characterized by inflammatory demyelination and progressive neurodegeneration. Although current disease-modifying therapies modulate peripheral autoimmune responses, they are insufficient to fully prevent tissue specific neuroinflammation and long-term neuronal and oligodendrocyte loss. Growing evidence implicates various regulated cell death (RCD) pathways, including apoptosis, necroptosis, pyroptosis, and ferroptosis, not only as downstream consequences of chronic inflammation, but also as active drivers of demyelination, axonal injury, and glial dysfunction in MS.
View Article and Find Full Text PDFJ Am Soc Mass Spectrom
September 2025
Department of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.
An ongoing goal of top-down mass spectrometry is to increase the performance for larger proteins. Using higher energy activation methods, like 193 nm ultraviolet photodissociation (UVPD), offers the potential to cause more extensive fragmentation of large proteins and thereby yield greater sequence coverage. Obtaining high sequence coverage requires confident identification and assignment of fragment ions, and this process is hampered by spectral congestion and low signal-to-noise ratio (S/N) of the fragment ions.
View Article and Find Full Text PDFSci Bull (Beijing)
August 2025
Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing 101408, China.
Cognitive control is fundamental to human goal-directed behavior. Understanding its trajectory across the lifespan is crucial for optimizing cognitive function throughout life, particularly during periods of rapid development and decline. While existing studies have revealed an inverted U-shaped trajectory of cognitive control in both behavioral and anatomical domains, the age-related changes in functional brain activities remain poorly understood.
View Article and Find Full Text PDF