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| http://dx.doi.org/10.1016/j.echo.2024.10.014 | DOI Listing |
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Background Gestational diabetes mellitus (GDM) has been increasingly associated with heightened cardiovascular and thrombotic risk. This study aimed to evaluate hemostatic and metabolic profiles in women with GDM to explore early markers of vascular dysfunction. Methods A retrospective cross-sectional study was conducted among 250 pregnant women diagnosed with GDM between December 2022 and October 2023 at multiple tertiary healthcare facilities in Pakistan.
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: Thrombophilia is a prothrombotic disorder that can affect pregnancy outcomes, potentially leading to maternal complications, fetal growth restriction, and adverse perinatal events. However, the precise relationship between thrombophilia and these outcomes remains under investigation, and the impact of hematological, renal, hepatic, and coagulation alterations in thrombophilic pregnancies is not yet fully understood. This study aims to examine the maternal and neonatal consequences of thrombophilia by analyzing key laboratory parameters and perinatal outcomes in affected pregnancies.
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