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We propose Gumbel Noise Score Matching (GNSM), a novel unsupervised method to detect anomalies in categorical data. GNSM accomplishes this by estimating the scores, i.e., the gradients of log likelihoods w.r.t. inputs, of continuously relaxed categorical distributions. We test our method on a suite of anomaly detection tabular datasets. GNSM achieves a consistently high performance across all experiments. We further demonstrate the flexibility of GNSM by applying it to image data where the model is tasked to detect poor segmentation predictions. Images ranked anomalous by GNSM show clear segmentation failures, with the anomaly scores strongly correlating with segmentation metrics computed on ground-truth. We outline the score matching training objective utilized by GNSM and provide an open-source implementation of our work.
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http://dx.doi.org/10.3389/frai.2024.1441205 | DOI Listing |
Cardiovasc Revasc Med
September 2025
Division of Vascular Surgery, Cardiovascular Center, Tufts Medical Center, Boston, MA, USA; Tufts University School of Medicine, Boston, MA, USA. Electronic address:
Background: protamine sulfate is used to reduce bleeding risk after Carotid Artery Stenting (CAS), but its efficacy in personalized patient settings remains underexplored. This study aims to identify factors associated with greater benefits from protamine sulfate following CAS.
Methods: A retrospective review of Vascular Quality Initiative (VQI) data (2016-2022) identified patients undergoing CAS, divided into Transfemoral CAS (TF-CAS) and Transcarotid artery revascularization (TCAR) groups.
Encephale
September 2025
Psychiatry 'A' Department, Hedi Chaker University Hospital, Sfax, Tunisia.
Aims: Cannabis is widely used for various reasons, including its effects on sexuality. It has significant short- and long-term health consequences. However, its impact on sexual health remains uncertain.
View Article and Find Full Text PDFMed
September 2025
Department of Rheumatology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200000, China; Academy for Clinical Innovation and Translation of Shanghai, Shanghai 200000, China. Electronic address:
Background: Anti-melanoma differentiation-associated gene 5-positive dermatomyositis (MDA5+ DM) with rapidly progressive interstitial lung disease (RPILD) is a fatal disease. Although Janus kinase inhibitors (JAKi) hold their promise in treating MDA5+ DM, regimen for RPILD is still urgently needed to improve the adverse prognosis.
Methods: Based on a large inception cohort of MDA5+ DM, patients with RPILD (oxygen index [OI] < 300 within the first 3 months of disease duration) were included.
Soc Sci Med
September 2025
Department of Sociology and Criminology, State University of New York at Buffalo, 430 Park Hall, USA.
As the prevalence of Alzheimer's disease and related dementias (ADRD) rises in the United States, understanding social determinants of cognitive health has become increasingly important. While a robust literature highlights the downward transmission of (dis)advantage across generations, emerging research suggests that this transmission may also flow upwards from offspring to parents. Drawing on data from the National Longitudinal Study of Adolescent to Adult Health (Add Health) parent sample, we examine the association between adult children's educational attainment and parental cognitive functioning at midlife using a propensity score matching approach to account for selection on observed confounders.
View Article and Find Full Text PDFEarly Hum Dev
September 2025
Sivas Cumhuriyet University, Faculty of Medicine, Department of Pediatric Endocrinology, Sivas, Türkiye.
Background: The appearance of pubic or axillary hair before the age of eight in girls or nine in boys, without other signs of puberty, is defined as premature adrenarche (PA) and may be an early sign of the metabolic syndrome. The second to fourth digit ratio (2D:4D), thought to reflect prenatal androgen exposure, has been associated with a variety of behavioral, metabolic, and hormonal conditions.
Objective: To evaluate the relationship between 2D:4D digit ratios and anthropometric, metabolic, and hormonal parameters in children with PA.