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Aim: To evaluate the visual outcomes of standard amblyopic treatment add-on training perceptual learning in refractive amblyopic children and to identify the risk factors for treatment failure.
Methods: Retrospective charts were reviewed in children with refractive amblyopia who received standard treatment and add-on Cambridge Visual Stimulator (CAM) training. The add-on CAM group that was enrolled had worn full-corrected glasses for at least 2mo before training. A control group received only the standard treatment. Treatment success was defined as best-corrected visual acuity (BCVA) ≥20/25. The age, sex, initial BCVA, refractive errors, sessions and duration of training, and final BCVA were recorded.
Results: A total of 209 children (129 children in add-on CAM group and 80 children in control group) were enrolled. Seventy-six percent of unilateral and 87% of bilateral amblyopic children achieved treatment success. In children with unilateral or bilateral moderate amblyopia, the duration to reach BCVA ≥20/25 was significantly shorter in add-on CAM group than in control group. Poor initial BCVA (<0.001) and high astigmatism (=0.007) were risk factors for treatment failure after add-on CAM training. Age, sex, and types of refractive error were not associated with treatment success.
Conclusion: Add-on CAM training is an effective strategy for visual improvement and can shorten the treatment course when the effect of standard treatment is limited in amblyopic children.
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http://dx.doi.org/10.18240/ijo.2024.10.11 | DOI Listing |
Bioengineering (Basel)
December 2024
Department of Oral and Craniomaxillofacial Surgery, Ghent University Hospital, 9000 Ghent, Belgium.
Head and neck reconstruction following ablative surgery results in alterations to maxillofacial anatomy and function. These postoperative changes complicate dental rehabilitation. An innovative modular, stackable guide system for immediate dental rehabilitation during mandibular reconstruction is presented.
View Article and Find Full Text PDFInt J Ophthalmol
October 2024
Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung City 833, Taiwan, China.
Aim: To evaluate the visual outcomes of standard amblyopic treatment add-on training perceptual learning in refractive amblyopic children and to identify the risk factors for treatment failure.
Methods: Retrospective charts were reviewed in children with refractive amblyopia who received standard treatment and add-on Cambridge Visual Stimulator (CAM) training. The add-on CAM group that was enrolled had worn full-corrected glasses for at least 2mo before training.
Schizophr Res
April 2024
Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK. Electronic address:
Schizophrenia is one of the most debilitating mental disorders, and its diagnosis and treatment present significant challenges. Several clinical trials have previously evaluated the effectiveness of simvastatin, a lipid-lowering medication, as a novel add-on treatment for schizophrenia. However, treatment effects varied highly between patients and over time.
View Article and Find Full Text PDFJ Prosthet Dent
March 2024
Associate Professor, Division of Comprehensive Oral Health, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC. Electronic address:
Statement Of Problem: Resin-bonded prostheses, including interim resin-bonded prostheses, are effective in preserving tooth structure compared with other types of fixed dental prostheses for the replacement of missing teeth. However, loss of retention remains a notable concern with these types of prostheses.
Purpose: The purpose of this in vitro study was to investigate the influence of glass-ceramic type, resin type, and surface finish on the shear bond strength (SBS) to the CAD-CAM ceramics used to fabricate interim resin-bonded prostheses.
Plants (Basel)
April 2023
K.A. Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, 127276 Moscow, Russia.
The intracellular accumulation of inorganic carbon (C) by microalgae and cyanobacteria under ambient atmospheric CO levels was first documented in the 80s of the 20th Century. Hence, a third variety of the CO-concentrating mechanism (CCM), acting in aquatic photoautotrophs with the C photosynthetic pathway, was revealed in addition to the then-known schemes of CCM, functioning in CAM and C higher plants. Despite the low affinity of ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) of microalgae and cyanobacteria for the CO substrate and low CO/O specificity, CCM allows them to perform efficient CO fixation in the reductive pentose phosphate (RPP) cycle.
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