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| http://dx.doi.org/10.1016/j.arth.2024.10.050 | DOI Listing |
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Background: Postoperative edema and ecchymosis are common concerns following rhinoplasty, often prolonging recovery and affecting patient satisfaction. Systemic dexamethasone is widely used to reduce these complications, and topical tranexamic acid has recently gained attention. However, no study has directly compared their efficacy or evaluated their combined effect.
View Article and Find Full Text PDFHypovolemic and hemorrhagic shock are life-threatening conditions that, if untreated, rapidly lead to multi-organ failure and death. These conditions result from significant intravascular fluid or blood loss, causing critical organ hypoperfusion. The underlying pathophysiology involves complex hemodynamic, inflammatory, and coagulation disturbances that may progress to irreversible organ dysfunction.
View Article and Find Full Text PDFHemostatic effect of oxidized regenerated cellulose vs. topical tranexamic acid in total knee arthroplasty-a prospective randomized controlled trial.
Front Surg
January 2025
Department of Knee Joint Surgery, Xi'an Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Aims: This study compared the hemostatic effects and complications of oxidized regenerated cellulose (ORC) and topical TXA in total knee arthroplasty (TKA), thus providing a reference for the use of ORC as an alternative hemostatic agent to TXA in TKA.
Methods: A total of 105 patients were included in this study and randomized into blank control, ORC, and TXA groups. The primary outcomes were total blood loss, hemoglobin drop (Hb drop), transfusion rates, and incidence of thrombosis.
Impact of Topical Tranexamic Acid on Bleeding Control in Rhinoplasty.
World J Plast Surg
January 2024
Anesthesiology and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Background: Hemorrhage during rhinoplasty may impair the surgeon's visibility. Our objective was to examine the impact of subcutaneously administered Tranexamic acid (TXA) on bleeding during rhinoplasty.
Methods: A three-blind randomized clinical trial including 60 patients undergoing nose surgery was conducted to compare the effects of two different anesthetic solutions on surgery results.
The efficacy and application of tranexamic acid in emergency medicine: Emergency Medicine Association of Türkiye clinical policy- 2024.
Turk J Emerg Med
October 2024
Department of Medical Education, Acibadem Mehmet Ali Aydınlar University, School of Medicine, Istanbul, Türkiye.
The clinical policy of the Emergency Medicine Association of Türkiye (EMAT) provides guidance on the use of tranexamic acid (TXA) in emergency settings. TXA, an antifibrinolytic drug, is used to control bleeding by inhibiting plasminogen. Its applications have expanded from hemophilia and severe menstrual bleeding to include various forms of trauma and surgery-related bleeding.
View Article and Find Full Text PDF