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Hepatocellular carcinoma (HCC) rupture is a severe complication, yet there is limited literature on cases complicated by subsequent non-occlusive mesenteric ischemia (NOMI). A 77-year-old man presented to our hospital with abdominal pain and shock. Arterial phase computed tomography (CT) hepatic arteriography revealed a 77-mm HCC in the left lobe with active extravasation, and the feeding artery was embolized. Although the abdominal pain initially subsided after the procedure, it recurred the next day. A contrast-enhanced CT scan revealed pneumatosis intestinalis and decreased enhancement of the small intestinal wall. The patient underwent resection of the affected segment of the small intestine and was ultimately diagnosed with NOMI based on pathological findings. This is the first reported case of NOMI following HCC rupture. Given the high mortality associated with these conditions, clinicians should be aware of this rare complication and ensure comprehensive evaluation and timely intervention to improve patient outcomes.
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http://dx.doi.org/10.1007/s12328-024-02051-5 | DOI Listing |
In Vivo
August 2025
Department of Gastroenterological Surgery, Saitama Medical University International Medical Center, Saitama, Japan.
Background/aim: Non-occlusive mesenteric ischemia (NOMI) is a rare and highly fatal disease characterized by intestinal ischemia or necrosis despite the absence of obstruction of the mesenteric vessels. This research aimed to investigate the risk factors for 30-day mortality of NOMI after emergency surgery.
Patients And Methods: We analyzed 42 consecutive patients who underwent emergency surgery for NOMI from April 2015 to August 2022.
Intern Med
August 2025
Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Japan.
An 81-year-old man was brought to our institution because of general fatigue, loss of appetite, and decreased consciousness. Based on the clinical findings, the patient was diagnosed with diabetic ketoacidosis (DKA) and started on insulin therapy. Two days after normalization of the ketone body level, he developed a high fever and abdominal pain.
View Article and Find Full Text PDFPLoS One
August 2025
Department of Research and Development, Norwegian Air Ambulance Foundation, Oslo, Norway.
Background: Both cardiopulmonary resuscitation (CPR) and ischaemia could lead to abdominal organ injury. However, the importance of abdominal injury in cardiac arrest remains uncertain. We aimed to systematically review indexed literature to describe incidence of abdominal injury after non-traumatic cardiac arrest and associations with outcome.
View Article and Find Full Text PDFCureus
July 2025
Cardiology, Advocate Lutheran General Hospital, Park Ridge, USA.
Non-occlusive mesenteric ischemia (NOMI) is a rare complication after transcatheter aortic valve replacement (TAVR), with a poorly understood pathogenesis. We present the case of a 79-year-old female with a history of surgically repaired abdominal aortic aneurysm (AAA) and stable thoracic aortic aneurysm (TAA) who developed NOMI after TAVR, resulting in extensive bowel necrosis and patient mortality. Our case highlights the special attention that must be paid to patients with a history of endovascular interventions prior to TAVR due to the risk of postprocedural NOMI.
View Article and Find Full Text PDFAim: Hydrogen inhalation therapy, a novel therapy for reducing oxidative stress in post-cardiac arrest syndrome, was beneficial for superior mesenteric artery (SMA) occlusion. We assessed the efficacy and feasibility of hydrogen inhalation therapy in swine models of critically ill conditions leading to non-occlusive mesenteric ischemia (NOMI) without acute surgical intervention.
Methods: NOMI was induced in eight 3- to 4-month-old female swine under general anesthesia.