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EoE Recurrence on PPI Maintenance Therapy: You Do Not Know if You Do Not Look! | LitMetric

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Article Abstract

Background And Aims: Data regarding histologic recurrence of EoE on PPI maintenance therapy are lacking.

Methods: Retrospective review of 101 patients with histologic PPI-responsive EoE.

Results: 52/101 (51%) patients underwent follow-up EGD with biopsies. Of the 52 patients, 29 (56%) maintained histologic remission and 23 (44%) had histologic recurrence. 21 (40%) patients maintained BID PPI, 20 (39%) tapered to QD, and 11 (21%) had discontinued PPI. Of the 21 patients on BID PPI, 7 (33%) had histologic recurrence, of which 6 (86%) were asymptomatic.

Conclusions: Patients on PPI therapy for EoE benefit from serial clinical, endoscopic, and histologic surveillance.

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Source
http://dx.doi.org/10.1007/s10620-024-08676-3DOI Listing

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