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The most common form of replacement therapy for end-stage renal disease (ESRD) is hemodialysis, and the adequacy of hemodialysis is strongly associated with the quality of life and long-term survival of patients. Kt/V is currently one of the most important indicators for evaluating the adequacy of hemodialysis. There are many methods for measuring Kt/V, such as blood collection and measurement, dialysate measurement, bioresistive resistance, WinNonlin software analysis, and artificial intelligence. There are different views on the importance of Kt/V as an indicator of the adequacy of hemodialysis. This article provides a literature review of the various methods of measuring Kt/V and on different perspectives on Kt/V as an evaluation of hemodialysis adequacy.
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http://dx.doi.org/10.1111/1744-9987.14217 | DOI Listing |
Objective: This retrospective longitudinal cohort study aimed to compare the clinical differences between patients with diabetic nephropathy (DN) and non-diabetic nephropathy (NDN) undergoing maintenance hemodialysis and to investigate the influencing factors and clinical significance of phase angle (PhA) in DN patients.
Materials And Methods: Hemodialysis patients (n = 48), including 23 with DN and 25 with NDN, were enrolled in this study. Body composition parameters were assessed using bioelectrical impedance analysis (BIA), and various biochemical indices were collected.
Neuropsychiatr Dis Treat
August 2025
Blood Purification Center, Nanjing BenQ Medical Center, the Affiliated BenQ Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, People's Republic of China.
Introduction: Cognitive frailty is increasingly recognized among older adults receiving maintenance hemodialysis (MHD), yet effective screening tools tailored for this population are lacking. This study aimed to develop a predictive model to identify MHD patients of advanced age who are at high risk for cognitive frailty, thereby facilitating early detection and intervention.
Methods: A cross-sectional study was conducted between February and December 2024, enrolling 223 older individuals undergoing MHD at a tertiary hospital in Nanjing, China.
Afr J Lab Med
July 2025
Department of Chemical Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Background: Chronic kidney disease is a global health crisis, and delays in laboratory testing worsen outcomes. Point-of-care testing (POCT) has shown utility in various settings, but its performance at high creatinine levels seen in advanced chronic kidney disease is variable.
Objective: We evaluated the analytical and clinical performance of the Nova Stat Profile Prime Plus (SPP+) point-of-care analyser among patients on maintenance haemodialysis.
Nephrol Dial Transplant
August 2025
Associazione Nefrologica Gabriella Sebastio, Martina Franca, Italy.
Background: Interest in incremental haemodialysis (HD) is growing. The urea-based adequacy criterion of incremental HD is founded on two equivalent continuous clearances (ECC), i.e.
View Article and Find Full Text PDFBMC Nephrol
August 2025
Department of Nursing, Changsha Central Hospital, Affiliated to University of South China, Changsha, 410004, China.
Background: Intradialytic exercise interventions improve dialysis efficacy; however, their comparative efficacy remains unclear, limiting evidence-based clinical practice.
Objective: To systematically review and compare the effects of different intradialytic exercises on dialysis adequacy in patients undergoing hemodialysis.
Methods: A systematic search was conducted in PubMed, EMBASE, Web of Science, and the Cochrane Library for randomized controlled trials evaluating the efficacy of intradialytic exercise on dialysis adequacy in patients undergoing hemodialysis.