98%
921
2 minutes
20
Associations between adversity and youth psychopathology likely vary based on the and of experiences. Major theories suggest that the impact of childhood adversity may either be in type (the more types of adversity, the worse outcomes) or in timing (the longer exposure, the worse outcomes) or, alternatively, concerning the type (e.g., parenting, home, neighborhood) or the timing of adversity (e.g., specific developmental periods). In a longitudinal sample from the Future of Families and Wellbeing Study ( = 4,210), we evaluated these competing hypotheses using a data-driven structured life-course modeling approach using risk factors examined at child age 1 (infancy), 3 (toddlerhood), 5 (early childhood), and 9 (middle childhood). Results showed that exposures to more types of adversity for longer durations (i.e., cumulative in both type and timing) best predicted youth psychopathology. Adversities that occurred at age 9 were better predictors of youth psychopathology as compared to those experienced earlier, except for neglect, which was predictive of internalizing symptoms when experienced at age 3. Throughout childhood (across ages 1-9), aside from the accumulation of all adversities, parental stress and low collective efficacy were the strongest predictors of internalizing symptoms, whereas psychological aggression was predictive of externalizing symptoms.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11965435 | PMC |
http://dx.doi.org/10.1017/S0954579424001512 | DOI Listing |
Psychol Med
September 2025
Faculty of Behavioral and Social Sciences, Department of Pedagogy and Educational Sciences, https://ror.org/012p63287University of Groningen, Groningen, The Netherlands.
Background: Depression runs in families, with both genetic and environmental mechanisms contributing to intergenerational continuity, though these mechanisms have often been studied separately. This study examined the interplay between genetic and environmental influences in the intergenerational continuity of depressive symptoms from parents to offspring.
Methods: Using data from the Dutch TRAILS cohort ( = 2201), a prospective, genetically informed, multiple-generation study, we examined the association between parents' self-reported depressive symptoms (reported at mean age of 41 years) and offspring depressive symptoms, self-reported nearly two decades later, in adulthood (mean age: 29 years).
Schizophr Res
September 2025
Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Psychiatry, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan. Electronic address:
Background: Youth is a critical period for brain development, yet first-episode schizophrenia (FES) during this stage remains understudied, particularly concerning the role of vascular endothelial growth factor (VEGF) in schizophrenia-related psychopathology and cognitive dysfunction.
Methods: This study enrolled 32 youth (ages 12-24) with FES and 35 age-/sex-matched healthy controls. Serum VEGF levels were measured using enzyme-linked immunosorbent assay.
J Res Adolesc
September 2025
Department of Child and Youth Studies, Brock University, St. Catharines, Ontario, Canada.
The Perfectionism Social Disconnection Model (PSDM) contends that perfectionism predicts psychopathology via social disconnection and has received support in adult and adolescent samples. However, little is known about the role of online connection. Consequently, this work tested whether online social connection and in-person social support uniquely mediate the relation between perfectionistic self-presentation and depressive symptoms among adolescents.
View Article and Find Full Text PDFBMJ Open
September 2025
Psychologial Neuroscience Laboratoy (PNL), Psychology Research Center (CIPSI), School of Psychology, University of Minho, Braga, Portugal
Introduction: Adolescence and youth are periods of significant maturational changes, which seem to involve greater susceptibility to disruptive events in the brain, such as binge drinking (BD). This pattern-characterised by repeated episodes of alcohol intoxication-is of particular concern, as it has been associated with significant alterations in the developing brain. Recent evidence indicates that alcohol may also induce changes in gut microbiota composition and that such disturbances can lead to impairments in both brain function and behaviour.
View Article and Find Full Text PDF