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http://dx.doi.org/10.1016/S2589-7500(24)00178-X | DOI Listing |
Clin Transl Sci
September 2025
Food and Drug Administration, Silver Spring, Maryland, USA.
Since the first decentralized clinical trial (DCT) was conducted in 2011, there has been an increased usage of DCT due to its benefits of patient-centricity and generalizability of findings. This trend was further expedited by the global COVID-19 pandemic. We identified 23 case studies across various therapeutic areas and grouped them into different categories according to their purposes-by necessity, for operational benefits, to address unique research questions, to validate innovative digital endpoints, or to validate decentralization as a clinical research platform.
View Article and Find Full Text PDFRen Fail
December 2025
Department of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Large language models (LLMs) represent a transformative advance in artificial intelligence, with growing potential to impact chronic kidney disease (CKD) management. CKD is a complex, highly prevalent condition requiring multifaceted care and substantial patient engagement. Recent developments in LLMs-including conversational AI, multimodal integration, and autonomous agents-offer novel opportunities to enhance patient education, streamline clinical documentation, and support decision-making across nephrology practice.
View Article and Find Full Text PDFAnal Chim Acta
November 2025
Key Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry and Materials Science, Hebei University, Baoding, 071002, PR China; Engineering Research Center of Ecological Safety and Conservation in Beijing-Tianjin-Hebei (Xiong'an New Area) of Ministry of Education, Bao
Background: In the contemporary era of rapid digital advancement, information security is closely associated with our daily life. From personal information to state secrets, all domains are intricately linked with information. Consequently, the significance of information security has garnered growing attention from an ever-increasing number of individuals.
View Article and Find Full Text PDFActa Psychol (Amst)
September 2025
University Sains Malaysia, 11800, Penang, Malaysia; Berlin School of Business and Innovation (BSBI), Berlin, Germany. Electronic address:
This study examines the impact of AI-enhanced transformational leadership on IT professional burnout among Chinese IT professionals while investigating the mediating role of AI learning self-efficacy and the moderating effects of AI-enabled work practices and organizational AI-communication adequacy. Drawing on the technology-organization-environment (TOE) Framework, our research integrates traditional transformational leadership with emerging AI applications, offering a comprehensive model for understanding how digital leadership influences employee well-being in high-pressure IT environments. Data collected from 511 IT professionals across major Chinese technology hubs were analyzed using SMART-PLS.
View Article and Find Full Text PDFActa Psychol (Amst)
September 2025
College of Hospitality and Tourism Management, Sejong University, 98 Gunja-Dong, Gwanjin-Gu, Seoul 143-747, Republic of Korea.
An industrial trend regarding a surging amount of attention to central bank digital money (CBDM) by government bodies and consumers has recently been observed. The aim of this study is to assess the roles of the antecedents and moderators, which include fear of missing out, confidence of CBDM in the digitalized era, and attachment to CBDM, in regards to predicting CBDM adoption within the framework of the theory of planned behavior and the five phases of the consumer adoption process in order to keep up to date with this rapidly changing industrial trend. Data sets from 515 respondents were collected for empirical analyses via an online panel survey in order to achieve the research objectives.
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