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Children/adolescents with cancer can develop adverse effects impacting gross motor function. There is a lack of gross motor function assessment tools that have been validated for this population. The aim of this multicenter cross-sectional study was to preliminary validate the 88-item Gross Motor Function Measure (GMFM-88) for use in children/adolescents with cancer, exploring internal consistency and floor/ceiling effect. Inclusion criteria regarded children/adolescents diagnosed with cancer on treatment or <1 year off therapy. The internal consistency was assessed using Cronbach's α, and the floor-ceiling effects were calculated through percentage. This study involved 217 participants with heterogeneous neoplasm conditions. Internal consistency was good, with a Cronbach's α of 0.989. Floor-ceiling effect analysis reveals that several items obtained a dichotomous scoring distribution in each of the five sub-scales of the GMFM-88. This can be explained by the heterogeneous clinical characteristics of the target population. The preliminary validation of GMFM-88 in a group of children/adolescents affected by cancer suggests that some items are not able to discriminate between different gross motor function levels, and therefore it does not represent an informative tool to measure gross motor function in children with cancer. Future research is needed to define which ones could be more useful for clinical practice.
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http://dx.doi.org/10.3390/curroncol31090390 | DOI Listing |
Int J Rehabil Res
September 2025
Visual Impairments, Faculty of Education and Rehabilitation Sciences, University of Zagreb, Zagreb, Croatia.
The Visual Function Classification System (VFCS) provides a standardised framework for grading visual functioning in children with cerebral palsy (CP). This study evaluated the reliability and construct validity of the Croatian VFCS, and its ability to distinguish visual functioning across CP subtypes and functional classifications. Ninety-five children with CP (mean age: 11.
View Article and Find Full Text PDFQual Life Res
September 2025
The Kids Research Institute Australia, The University of Western Australia, P.O. Box 855, West Perth, WA, 6872, Australia.
Purpose: CDKL5 deficiency disorder (CDD) is a rare developmental and epileptic encephalopathy. Greater understanding of the smallest meaningful improvements for individuals with CDD in clinical trials and practice is needed for a person-centred approach to treatment efficacy. This study explored how parent/caregivers of people with CDD understood meaningful improvements and described change for priority functional domains including communication, gross motor, fine motor, feeding.
View Article and Find Full Text PDFS Afr J Commun Disord
August 2025
Department of Speech-Language Pathology and Audiology, Faculty of Humanities, University of Pretoria, Pretoria.
Background: Small infants face more developmental risks than their full-term peers, necessitating early intervention and long-term monitoring.
Objectives: This study examined the longitudinal developmental and hearing outcomes of small infants attending a high-risk clinic in a South African low-income community setting.
Method: A short-term longitudinal within-subject descriptive study design was employed, where 28 participants underwent hearing and developmental screenings and assessments at two follow-up appointments (T1 and T2), at 6- and 12-month corrected age.
Medicine (Baltimore)
September 2025
Department of Orthopedics and Traumatology, Brazilian Association for the Welfare of the Handicapped Children (AACD), São Paulo, SP, Brazil.
Hip dysplasia in cerebral palsy (CP) is a common and severe problem, especially among nonambulatory patients. A likely cause is muscular imbalance and developmental bone changes leading to a progressive extrusion of the femoral head from the acetabulum. The ideal surgical treatment aims to reduce the dislocated hip to improve pain, positioning, and function.
View Article and Find Full Text PDFFront Public Health
September 2025
Physical Education Institute, Shanxi University, Taiyuan, China.
Introduction: To evaluate the efficacy of CHIN-SKIP sports game intervention in enhancing motor ability among preschool children aged 5-6 years.
Methods: From September to December 2024, a total of 60 preschool children (aged 5-6 years) were randomly selected from two large classes at DM kindergarten and equally allocated to either the experimental group ( = 30) or control group ( = 30), with balanced gender distribution between groups. The experimental group received the CHIN-SKIP sports game intervention, while the control group participated in standard kindergarten physical activities.