98%
921
2 minutes
20
Objective: To better characterize the cochlear apex in relation to surgically relevant landmarks to guide surgeons and improve procedural success of apical electrode placement.
Study Design: Retrospective image analysis.
Setting: Tertiary referral center.
Patients: Cochlear implant recipients with available preoperative computed tomography (CT) imaging.
Intervention: None.
Main Outcome Measure: Cochlear dimensions and cochlear apex distance measures to surgically relevant middle ear landmarks and critical structures.
Results: Eighty-two temporal bone CT scans were analyzed utilizing multiplanar reformats. The average lateral width of promontory bone over the cochlear apex was 1.2 mm (standard deviation [SD], 0.3). The anteroposterior distance from the round window (avg, 4.2 mm; SD, 0.5), oval window (avg, 3.3 mm; SD, 0.3), cochleariform process (avg, 2.3; SD, 0.5), and superior-inferior distance from the cochleariform process (avg, -0.9; SD, 0.8) to the cochlear apex were measured. The relationship of the cochlear apex to critical structures was highly variable.A newly developed stapes vector was created and found to mark the posterior/superior boundary of the apex in 94% of patients. When a vector parallel to the stapes vector was drawn through the round window, it marked the anterior/inferior boundary of the cochlear apex in 89% of patients.
Conclusions: This study assists in characterizing cochlear apex anatomy and its relation to surrounding structures as a means of improving procedural accuracy and reducing trauma during apical cochleostomy. Understanding both distance relationships and expected boundaries of the apex could help to inform future surgical approaches.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11424059 | PMC |
http://dx.doi.org/10.1097/ONO.0000000000000060 | DOI Listing |
Neurobiol Aging
August 2025
Department of Otorhinolaryngology/Head and Neck Surgery, University Medical Center Groningen, University of Groningen, PO Box 30.001, Groningen 9700 RB, the Netherlands; The Research School of Behavioural and Cognitive Neurosciences, University of Groningen, PO Box 30.001, Groningen 9700 RB, the Net
Presbycusis, or age-related hearing loss, is a prevalent condition characterized by progressive auditory decline, significantly impacting quality of life in older adults. While sensorineural damage has been widely studied, degeneration of the stria vascularis (SV) remains underexplored despite its essential role in cochlear ion homeostasis. The SV is organized into three cellular layers-marginal, intermediate, and basal cells-each with distinct functions critical for maintaining the endocochlear potential.
View Article and Find Full Text PDFAnat Rec (Hoboken)
July 2025
Department of Biomedical Sciences, Northeast Ohio Medical University, Rootstown, Ohio, USA.
The bony labyrinth of the petrosal bone, a distinctive feature of mammal skulls, is often identified in micro-computed tomography imaging to infer species' physiological and ecological traits. When done as part of a comparative study, one individual specimen is normally considered representative of a species, and intraspecific variation is considered low. Yet tests of intraspecific variability have been performed on few species and on limited morphological traits.
View Article and Find Full Text PDFJ Clin Med
July 2025
Hearing Research and Cochlear Implant Laboratory, Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Cochlear implantation is widely used to provide auditory rehabilitation to individuals with severe-to-profound sensorineural hearing loss. However, electrode insertion during cochlear implantation leads to inner ear trauma, damage to sensory structures, and consequently, loss of residual hearing. There is very limited information regarding the target proteins involved in electrode insertion trauma (EIT) following cochlear implantation.
View Article and Find Full Text PDFDev Biol
October 2025
Department of Neurobiology, Spencer Fox Eccles School of Medicine at the University of Utah, Salt Lake City, UT, USA; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA, USA; Department of Otolaryngology - Head & Neck Surgery, Spencer Fox Eccles School of Medicine at the Un
The organ of Corti is divided into functional compartments responsible for hearing or cochlear amplification. A medial compartment containing inner hair cells innervated by Type I spiral ganglion neurons and a lateral compartment containing outer hair cells innervated by Type II spiral ganglion neurons. Supporting cells also differ, with lateral compartment pillar cells and Deiters' cells developing specialized cellular structures to support outer hair cell electromotility.
View Article and Find Full Text PDF