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http://dx.doi.org/10.1093/ehjcr/ytae498 | DOI Listing |
Intensive Care Med Exp
August 2025
Department of Intensive Care Medicine, Amsterdam University Medical Center, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands.
Background: Histones released in response to cellular injury are important mediators of organ failure and death in sepsis. Preclinical studies demonstrate that neutralization of histones in sepsis is associated with improved outcome. M6229 is a low-anticoagulant heparin able to neutralize histones.
View Article and Find Full Text PDFLasers Med Sci
May 2025
Xuan Wu Hospital of the Capital Medical University, Beijing, China.
Objectives: A New Ultra-Low Pulse width 355 nm Solid-State Laser Shows Superior Performance to 308 nm Lasers in Preclinical Trials. Real-world statistics, however, are currently scarce. The purpose of this study is to assess the CLA-355 nm laser system's clinical safety and feasibility in human trials.
View Article and Find Full Text PDFJAMA Cardiol
July 2025
Multimodal Imaging and Theranostic Lab, Cardiovascular Center, Korea University Guro Hospital, Seoul, South Korea.
Importance: Fluorescence lifetime imaging (FLIm) is a molecular imaging technique used to visualize the biochemical composition of atherosclerosis. Novel dual-modal imaging using optical coherence tomography (OCT)-FLIm has the potential to provide both microstructural and biocompositional information on coronary plaques; however, it needs validation for clinical application.
Objective: To investigate the clinical feasibility and safety of OCT-FLIm for characterizing plaque compositions in patients with coronary artery disease (CAD) undergoing revascularization therapy.
Eur Heart J Case Rep
September 2024
Department of Cardiovascular Medicine, Osaka Metropolitan University Graduate School of Medicine, 1-4-3 Asahimachi Abenoku, Osaka 545-8585, Japan.
EuroIntervention
September 2024
Klinik für Herz- und Kreislauferkrankungen, Deutsches Herzzentrum München, Technical University Munich, Munich, Germany.