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The rapid advancements in natural language processing, particularly with the development of Generative Pre-trained Transformer (GPT) models, have opened up new avenues for researchers across various domains. This review article explores the potential of GPT as a research tool, focusing on the core functionalities, key features, and real-world applications of the GPT-4 model. We delve into the concept of prompt engineering, a crucial technique for effectively utilizing GPT, and provide guidelines for designing optimal prompts. Through case studies, we demonstrate how GPT can be applied at various stages of the research process, including literature review, data analysis, and manuscript preparation. The utilization of GPT is expected to enhance research efficiency, stimulate creative thinking, facilitate interdisciplinary collaboration, and increase the impact of research findings. However, it is essential to view GPT as a complementary tool rather than a substitute for human expertise, keeping in mind its limitations and ethical considerations. As GPT continues to evolve, researchers must develop a deep understanding of this technology and leverage its potential to advance their research endeavors while being mindful of its implications.
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http://dx.doi.org/10.1007/s13139-024-00876-z | DOI Listing |
AJNR Am J Neuroradiol
September 2025
From the Department of Diagnostic Radiology (E.W., A.D., C.J.M., M.C., M.K.G.) and Department of Pathology (L.Y.B.), MD Anderson Cancer Center, Houston, TX, USA; Department of Radiology and Biomedical Imaging (L.T., J.M.J), Yale University, New Haven, CT, USA.
Background And Purpose: Brain imaging with MRI or CT is standard in screening for intracranial disease among ambulatory cancer patients. Although MRI offers greater sensitivity, CT is frequently employed due to its accessibility, affordability, and faster acquisition time. However, the necessity of routinely performing a non-contrast CT with the contrast-enhanced study is unknown.
View Article and Find Full Text PDFEcotoxicol Environ Saf
September 2025
Department of Veterinary Medicine, College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang, Guangdong 524088, China; South China Branch of National Saline-Alkali Tolerant Rice Technology Innovation Center Zhanjiang, Guangdong 524088, China. Electronic address:
Aflatoxin B1 (AFB1)-induced hepatotoxicity is a common toxic disease in poultry farming. However, there is currently a lack of effective pharmaceutical interventions for treating AFB1. Astaxanthin (AST), a natural carotenoid, exhibits potent antioxidant and immune-enhancing properties.
View Article and Find Full Text PDFDiabetes Care
September 2025
Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA.
Objective: This study aimed to evaluate the diabetic eye disease screening continuum at two academic centers and identify its barriers.
Research Design And Methods: We analyzed health records from the University of California, San Francisco and University of California, Irvine to identify primary care patients needing diabetic eye screening. We tracked referrals, screenings, diagnoses, and treatments to evaluate predictors and the impact of an automated referral system.
Ophthalmol Glaucoma
September 2025
Department of Ophthalmology and Visual Sciences, University of Michigan W.K. Kellogg Eye Center, Ann Arbor, Michigan. Electronic address:
Purpose: To investigate hand function and eye drop instillation success in adults with and without glaucoma.
Design: Cross-sectional pilot study.
Subjects: Adults aged ≥ 65 years with glaucoma who use eye drops daily and adults aged 65+ without glaucoma who do not regularly use eye drops.
Acta Neurochir (Wien)
September 2025
Department of Neurosurgery, Istinye University, Istanbul, Turkey.
Background: Recent studies suggest that large language models (LLMs) such as ChatGPT are useful tools for medical students or residents when preparing for examinations. These studies, especially those conducted with multiple-choice questions, emphasize that the level of knowledge and response consistency of the LLMs are generally acceptable; however, further optimization is needed in areas such as case discussion, interpretation, and language proficiency. Therefore, this study aimed to evaluate the performance of six distinct LLMs for Turkish and English neurosurgery multiple-choice questions and assess their accuracy and consistency in a specialized medical context.
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